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Gresham Plastic Packaging (Changzhou) Co., Ltd
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Gresham Plastic Packaging (Changzhou) Co., Ltd

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    info-china@gerresheimer.com

  • Phone

    18661195281

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    Building 3, Rail Transit Industrial Park, No. 355 Longjin Road, Changzhou City, Jiangsu Province

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World diabetes Day | Caring for sugar friends, starting from the "coat" of a pill
Date: 2025-11-14Read: 3


  November 14 is World diabetes Day. Today, more than 589 million people around the world live with diabetes. Every day, "sugar friends" cannot live without accurate blood glucose management - an insulin injection and an oral hypoglycemic drug are not only the key steps of treatment, but also their daily commitment to protecting health and embracing life.
Behind this persistence, the safe delivery of drugs is crucial. From production to use, pharmaceutical packaging materials serve as the first line of defense between drugs and patients, not only carrying the mission of ensuring drug stability, purity, and efficacy, but also directly affecting patients' medication experience and long-term compliance. High quality and high reliability primary packaging and drug delivery systems (such as insulin pens, pre filling syringes, etc.) are becoming a very important part of modern diabetes management.
  diabetes
Diabetes is a general term for a variety of metabolic diseases, and its common feature is that the blood sugar level increases due to insufficient insulin secretion and/or weakened insulin action in patients. From the medical point of view, diabetes can be divided into many types, the most important of which are type 1 and type 2 diabetes.
Insulin is an important peptide hormone secreted by human pancreatic beta cells, which not only participates in regulating cell growth and differentiation, but also plays a core role in blood glucose regulation. Its main function is to promote the uptake of glucose by tissue cells such as liver, muscle, and fat, and convert it into energy, thereby effectively reducing blood sugar levels. For patients with type 1 diabetes, exogenous insulin replacement therapy is a key means to maintain life because the body cannot synthesize insulin itself.
At the same time, in the field of treatment of type 2 diabetes (T2D), incretin analogues, namely GLP-1 receptor agonists, have become an important class of hypoglycemic drugs. Its mechanism of action is to simulate the physiological effects of endogenous hormones in the human body, such as glucagon like peptide-1 (GLP-1) and glucose dependent insulinotropic polypeptide (GIP). Compared to insulin therapy, GLP-1 receptor agonists can significantly reduce the incidence of side effects, decrease the risk of hypoglycemia, and bring more significant weight loss effects.
Based on the above different mechanisms and clinical needs, Graysheim, as a medical packaging system and solution provider, can provide a full range of product solutions covering insulin and incretin analogues in the field of diabetes treatment.
  Customized drug delivery device

For GLP-1 drugs based on cartridge bottles, this is the ideal choice: reusable pen injectors and cost-effective disposable injection pens not only ensure efficient delivery of active ingredients, but also significantly reduce injection pain.
In the field of pen injectors, our core competitiveness lies in a complete solution that combines high-quality reusable pen injectors with cost-effective disposable injection pens (including glass cartridges). With years of deep accumulation in the field of blood collection devices and blood collection needles, we have unique advantages in puncture technology - especially focusing on dermatological factors such as the impact of puncture process on pain perception. We are committed to ensuring efficient and precise administration of our customers' key products, such as insulin and other hormone active ingredients, while significantly reducing the pain experienced by patients during injections.
  Duma Twist Off plastic bottle

  The ideal choice for oral GLP-1 drugs.
  Product Features
-18 product sizes, bottle capacity 15~600ml
- Material: high-density polyethylene bottle body, polypropylene bottle cap
- Anti opening seal
- Available options:
- Child protective cover
The bottle cap has child protective properties and is easy for the elderly to use
- Can hold 1-6 grams of integrated and split desiccants
– Duma ®、 OneLiner ® Gaskets are available for the US market
- Some sizes can be equipped with thicker bottle bodies
- Registered with FDA, DMF type III, DMF code 12077



  Gx ® Advance series cartridge bottle

We offer two configurations: bulk (BULK) and no wash no extinguish (RTF). RTF products use baking silicification technology to effectively prevent the adsorption of active ingredients on the inner surface of the glass; It has passed multiple compatibility verifications of drug delivery devices and significantly improved the operational efficiency of filling and packaging production lines.
For over 60 years, we have been dedicated to the production of high-quality glass cartridge bottles, which fully meet the stringent requirements of modern filling systems on advanced production lines. Our product line includes 3.0 ml cartridge bottles made of Type I glass (other specifications can be customized as needed), with an annual production capacity of over 1 billion bottles.


  Gx ® Advance series penicillin bottles

The use of baking silicification process effectively prevents the adsorption of active ingredients on the glass surface, significantly improving the performance of the encapsulation production line. We offer two configuration options: Bulk and RTF.
Achieve higher encapsulation efficiency through excellent manufacturing processes
- Excellent performance and reliable performance on existing filling equipment
- Stricter AQL standards with fewer appearance defects
- More precise product dimensions
Reduce quality issues in incoming material inspection (quality begins at the source)
- Reduce contact between glass and glass
- Reduce contact between glass and metal
-100% online full inspection (size and appearance)
  Gx Advance Series RTF ® syringe
The ideal choice for GLP-1 and GIP drugs: With precise size control and strict performance standards, it ensures safe and stable operation in automatic injectors; Reliable silicification process significantly reduces start-up and sliding forces, optimizing injection smoothness and patient experience.

 1Needle syringe

Product Features
- Optimize the pulling force of the protective cap
- Fully compatible with automatic injectors and various safety systems
- Optimize needle design to effectively reduce the risk of needle hook and cap detachment
- Optional silicification scheme
- Tungsten content meets the specified standards
- Sterilize with ethylene oxide according to ISO 11135



  2Ruhr lock syringe
  
Product Features
- Screw cap closure design reduces the risk of protective cap detachment
- Optional silicification scheme
- Tungsten content meets the specified standards
- Sterilize with ethylene oxide according to ISO 11135