Graphene, as a strategically significant new type of nanomaterial, is on the eve of urgent breakthroughs in large-scale industrial applications. Graphene powder is the main form of graphene products in China, with broad industrial application prospects in various fields such as thermal conductive films, electrode materials for lithium-ion batteries, and anti-corrosion coatings. Graphene is often used in skincare products due to its strong adsorption, far-infrared emission, antibacterial and bacteriostatic properties, generation of negative ions, and natural environmental protection. This experiment compared the effects of three pretreatment methods, namely dry method, tetraacid method, and aqua regia extraction method, on the detection results of graphene and graphene containing shampoo samples, with reference to the "Technical Specification for Safety of Cosmetics", "GB/T 24533-2019 Graphite Negative Electrode Materials for Lithium ion Batteries", and literature review.