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SKID: Process Flow and Industry Application Analysis of Purified Water/Injection Water Distribution System
Date: 2025-12-31Read: 24
In industries such as pharmaceuticals, biotechnology, medical devices, and food and beverage, the quality of purified water and injection water directly affects the safety and effectiveness of products. The Skid mounted System (SKID), as a modular and integrated water treatment solution, has become an important key equipment in these industries due to its high efficiency, stability, and ease of management. This article will delve into the process flow of the purified water/injection water distribution system SKID and list its widespread applications in multiple industries.
1、 Process flow of SKID for purified water/injection water distribution system
The process design of SKID purified water/injection water distribution system aims to ensure high purity of water quality and microbial control, while meeting industry standards and regulatory requirements. The following are the core process steps:
1. Preprocessing stage
Multimedia filtration: Tap water first enters a multimedia filter, which removes particles, suspended solids, and some organic matter through media of different particle sizes (such as quartz sand and activated carbon), providing a relatively clean water source for subsequent treatment.
Activated carbon adsorption: further removes residual chlorine, odors, and organic matter from water to prevent damage to subsequent membrane treatment equipment caused by these substances.
Softening treatment: Remove calcium and magnesium ions from water through ion exchange resin, reduce water hardness, and prevent scaling.
2. Core processing stage
Reverse osmosis (RO): Using semi permeable membrane separation technology, it effectively removes ions, organic matter, and microorganisms from water, resulting in water quality close to purified water standards.
Electrodeionization (EDI): By combining ion exchange and electrodialysis techniques, trace ions in water are further removed, resulting in a significant increase in water resistivity and meeting the requirements of high standard purified water.
Distillation (Multi effect Distilled Water Machine): For injection water, purified water needs to be treated by a multi effect distilled water machine to remove heat sources and microorganisms through evaporation and condensation processes, ensuring sterile water quality.
3. Allocation and Circulation Stage
Storage and circulation: The treated purified water or injection water enters a stainless steel storage tank and is continuously circulated for 24 hours through a circulation pump and heat exchanger to maintain stable water temperature (such as insulation circulation above 70 ℃) and prevent microbial growth.
Online monitoring and control: The system is equipped with conductivity pH、 Online monitoring equipment for temperature, flow rate, etc. monitors water quality parameters in real-time to ensure that water quality meets the requirements of standards such as the Chinese Pharmacopoeia.
Disinfection and sterilization: Regularly use methods such as pasteurization, pure steam sterilization, or chemical disinfection to disinfect and sterilize the system, ensuring that it is in a sterile state.
4. Automation control stage
PLC and human-machine interface: The system adopts PLC (programmable logic controller) control and human-machine operation interface to achieve fully automatic operation, cleaning, online detection and other functions, improving operational convenience and system stability.
Remote monitoring and data management: Supports remote monitoring and data management, meets GMP certification requirements, and ensures data integrity and traceability.
2、 Industry application of SKID for purified water/injection water distribution system
The SKID purified water/injection water distribution system is widely used in multiple industries with strict water quality requirements due to its water treatment capacity and modular design
1. Pharmaceutical industry
Drug production: Purified water and injection water are important solvents and diluents in the drug production process, used to prepare oral or topical drug preparations, injections, eye drops, etc. The SKID system ensures that water quality meets the standards of the Chinese Pharmacopoeia, guaranteeing drug quality and patient safety.
GMP certification: Pharmaceutical companies need to comply with GMP (Good Manufacturing Practice) requirements. The SKID system simplifies the certification process and improves production efficiency through modular design and automated control.
2. Biotechnology industry
Biological product production: In the production of biological products such as vaccines, antibodies, and gene therapy products, purified water and injection water are used for cell culture, buffer preparation, and equipment cleaning. The high purity and sterility of SKID system are crucial for the activity and stability of biological products.
Laboratory research: Biotechnology laboratories require high-purity water for experimentation and analysis, and the SKID system provides stable water quality support to ensure the accuracy and reliability of experimental results.
3. Medical device industry
Medical device cleaning and sterilization: Purified water and injection water are used to clean and sterilize equipment during the production process of medical devices, ensuring the sterility and safety of medical devices. The disinfection and sterilization function of SKID system meets the strict standards of the medical device industry.
Implants and surgical instruments: For implants and surgical instruments, the SKID system provides high-purity water that helps reduce the risk of infection and improve patient treatment outcomes.
4. Food and beverage industry
Beverage production: In the production of beverages such as mineral water, purified water, and functional drinks, purified water is used for product preparation and packaging cleaning. The SKID system ensures that beverages have a pure and impurity free taste, enhancing product competitiveness in the market.
Food additives and ingredients: The production of food additives and ingredients requires high-purity water as a solvent, and the SKID system provides stable water quality support to ensure the safety and effectiveness of food additives.
5. Electronic industry
Semiconductor and electronic component cleaning: Ultra pure water is used in the cleaning and etching process of semiconductor and electronic component production to remove small particles and ions. Although the electronics industry has higher requirements for water quality, the SKID system can serve as a pre-treatment stage, providing a foundation for the subsequent preparation of ultrapure water.
3、 Conclusion
The SKID purified water/injection water distribution system provides reliable high-purity water solutions for industries such as pharmaceuticals, biotechnology, medical devices, food and beverage, and electronics through its modular design, efficient water treatment technology, and automated control. With the continuous improvement of water quality requirements and technological advancements in the industry, SKID system will play an important role in more fields, promoting the development of various industries towards higher quality and safety.