Jiangsu Guolang: Laboratory Small Dry Granulator

The GLZ-25 dry granulation machine is a self-developed experimental dry granulation machine by our company. This machine is the smallest dry granulation machine used for laboratory research and development, suitable for laboratories, intermediate experimental devices, and small-scale production. Only about 80 grams of dry powder are needed to achieve its formability. According to the principle of mechanical extrusion granulation process, the prepared dry powder or fine crystal raw materials with a certain amount of crystal water are extruded into thin sheets, and then processed through the granulation system and screened into particles of the desired size. Raw materials can be manually or vacuum fed into the hopper, transported and compressed by vertically placed feeding screws, and pushed to the bite angle of two extrusion rollers; Squeezing raw materials into thin sheets through horizontally placed rollers (the speed of the rollers determines the duration of the material's stay in the roller pressing zone); The pressure required for the material is linearly transmitted to the pressure roller through a hydraulic device, and the vertically arranged pressure rollers can ensure the density of the material. This machine is easy to install, disassemble, and clean.
According to different particle size requirements, the mesh size of the sieve in the equipment granulation system can be replaced with each other. Directly transforming powder raw materials into granular products that meet user requirements, without the need for any intermediates or additives. After granulation, the product has uniform particle size, significantly increased packing density, improved flowability, controlled dust flying, reduced powder waste, easy storage and transportation, and can control solubility, porosity, and specific surface area. Can be directly used for tablet pressing or capsule filling.

Especially suitable for granulation of drugs that cannot be granulated by traditional wet granulation and are unstable under humid and hot conditions. The dry granulation process can replace the assembly line input of wet granulation, saving manpower, material resources, and financial resources, and is a new type of energy-saving and environmentally friendly equipment.