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Types of drug packaging
Date: 2019-12-25Read: 6

Types of drug packaging

Nowadays, China's medical industry is gradually expanding, and the types of drugs are also increasing. According to the different physical and chemical properties of drugs, their packaging and storage methods are also different. The general packaging classifications on the market include: glass, metal, plastic, rubber, etc

(1)Glass is commonly used for packaging dosage forms such as injections, tablets, and oral solutions. Glass can be divided into sodium calcium silicate glass, low borosilicate glass, medium borosilicate glass, and high borosilicate glass according to their materials. The properties of materials with different compositions vary greatly, and the release of alkaline ions in glass should be emphasized to investigate its impact on the drug solutionpHThe impact; Release of harmful metal elements; Glass delamination under different temperatures (especially during freeze-drying) and pH conditions; Light blocking glass containing colorants is exposed to certain wavelengths of light, causing the drug to decompose; The adsorption of drugs by glass and issues such as pinholes and skewed bottle mouths in glass containers.

(2)Metals are commonly used in the packaging of ointments, aerosols, tablets, etc. Emphasis should be placed on investigating the corrosion of metals by drugs; The influence of metal ions on drug stability; The integrity of the metal coating before and after the experiment.

(3)Plastic is commonly used for packaging formulations such as tablets, capsules, injections, eye drops, etc. According to the material, it can be divided into high-density polyethylene, low-density polyethylene, polypropylene, polyethylene terephthalate, polyvinyl chloride, etc. Emphasis should be placed on the permeation of water vapor and the infiltration of oxygen; The leakage of water and volatile drugs; Transfer of lipophilic drugs and antibacterial agents to plastics; The adsorption of drugs by plastics; The interaction between solvents and plastics; The impact of additives in plastics and decomposition products during processing on drugs; And issues such as particles and sealing.

(4)Rubber is usually used as a plug or gasket for containers. According to the material, it can be divided into isoprene rubber, halogenated butyl rubber, and silicone rubber. Given the complexity of rubber formulations, the focus should be on examining the effects of the dissolution of various additives on the drug; The adsorption of drugs by rubber and the detachment of filling materials in solution. When conducting experiments on injections, oral liquid preparations, etc., they should be placed upside down and on the side so that the drug can fully come into contact with the rubber stopper.

The industry is gradually expanding, and quality must also keep up. The country has issued a series of standards for pharmaceutical packaging quality testing. Jinan Zhuyan Instrument actively responded to national policies and produced and invented a series of physical testing instruments for pharmaceutical packaging materials, meeting various needs for packaging quality testing. Subsequently, it actively occupied the market and fully gained recognition and approval from customers. It has now become a backbone force in the packaging testing industry