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E-mail
shchaosheng@163.com
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Phone
13853746518
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Address
No. 666, Yingkelei Industrial Park, 327 National Road, High tech Zone, Jining City
Jining Shuanghe Ultrasonic Equipment Co., Ltd
Process principle of continuous countercurrent ultrasonic extraction machine
Date: 2025-06-24Read: 6
Continuous countercurrent ultrasonic extraction machine is an efficient extraction equipment that combines continuous countercurrent extraction technology with ultrasonic enhancement. This technology is widely used in the fields of traditional Chinese medicine, food, and biology, suitable for large-scale industrial continuous production, and meets GMP standards. The core principle of its process is as follows:
1、 Principle of continuous countercurrent extraction
1. Reverse flow design
The medicinal herbs and extraction solvents move continuously in opposite directions inside the equipment: fresh medicinal herbs enter from one end of the equipment and gradually move towards the outlet; Fresh solvent is injected from the outlet end of the medicinal herbs and flows towards the inlet end of the medicinal herbs.
2. Greater concentration gradient
By reverse flow, the inlet end of the medicinal herb comes into contact with a high concentration extraction solution, and the outlet end comes into contact with a fresh solvent, forming a stable concentration difference that promotes the continuous dissolution of the target ingredient until the effective ingredients in the medicinal herb are fully extracted.
3. Efficient utilization of solvents
Minimize the amount of solvent used, and at the end of extraction, the residual components in the drug residue are extremely low. Some equipment is also equipped with a solvent recovery system (such as a condensing device) to further reduce consumption.
2、 Ultrasonic enhancement mechanism
1. Cavitation effect
Ultrasonic waves generate high-frequency vibrations in liquids, forming instantaneous high-pressure microbubbles that violently collapse (cavitation), instantly destroying the structure of plant cell walls and accelerating the release of active ingredients.
2. Mechanical vibration and disturbance
The mechanical waves transmitted by ultrasound cause high-frequency friction between medicinal herbs and solvents, enhancing the diffusion rate of components and shortening the diffusion path.
3. Low temperature and efficient extraction
Ultrasonic energy can be transmitted at room temperature or low temperature (40-60 ℃), avoiding the decomposition of thermosensitive components while maintaining extraction efficiency.
3、 Collaborative efficiency enhancement process
1. Dynamic counterflow+ultrasonic wall breaking: The concentration gradient formed by counterflow drives macroscopic mass transfer, while ultrasound accelerates cell rupture and component dissolution at the microscopic level. The synergistic effect of the two significantly improves extraction rate and yield.
2. Automation control: The equipment integrates a spiral conveying structure (single/double spiral), temperature control, and solvent flow regulation system to achieve continuous production and precise control of process parameters.
4、 Core advantages
1. Efficiency improvement: The extraction time has been reduced to 20-40 minutes, and the yield has increased by 50-500% compared to traditional methods;
2. Energy saving and consumption reducing: Reduce solvent usage and lower energy consumption through low-temperature operation;
3. Ingredient protection: Avoid deactivation of thermosensitive ingredients in low temperature environments, and be widely compatible with solvent systems such as water and ethanol.
