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Kerun Experimental Equipment (Shanghai) Co., Ltd

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Working principle and application fields of transdermal diffusion tester
Date: 2024-09-25Read: 2
The transdermal diffusion tester is a powerful and widely used experimental equipment, which is of great significance for promoting the development of drug research and development, cosmetics research and development, medical devices and other fields.
Working principle of transdermal diffusion tester
The working principle of the transdermal diffusion tester is based on the structure of the skin and the characteristics of the drug. The core part is the skin simulation membrane, which simulates the human skin environment to allow drugs to diffuse on the skin surface. The drug is delivered to one side of the skin simulation membrane through a precision pump system in the diffusion chamber, and then permeates and diffuses on both sides of the simulation membrane. The diffusion rate is directly proportional to the drug concentration gradient and inversely proportional to the diffusion distance. The transdermal diffusion device can also use temperature control technology to simulate human skin temperature and promote drug penetration and diffusion. At the same time, the equipped detection system monitors changes in drug concentration in real time to understand the dynamic process of drug penetration through the skin.
Application fields of transdermal diffusion tester
The transdermal diffusion tester has wide application value in multiple fields, including but not limited to:
Drug development: Evaluate the transdermal absorption performance and efficacy of new drugs.
Cosmetics research and development: Evaluate the paint penetration and bioavailability of cosmetic ingredients on the skin.
Medical devices: Evaluate the transdermal performance of medical devices such as patches and suppositories.