The core of maintenance for injection water storage tanks lies in regular cleaning and disinfection, strict monitoring of water quality, timely replacement of vulnerable parts, and ensuring that the equipment operating environment meets standards.
1. Regular cleaning and disinfection are key to ensuring water quality. It is recommended to clean with a 1% sodium hydroxide solution for 30 minutes every 3-6 months or based on water quality monitoring results, and then rinse with injection water until pH is neutral. Disinfection is carried out using pure steam at 121 ℃ for 30 minutes, and must be performed once a month or after a shutdown of more than 24 hours. If the microorganisms exceed the standard, they need to be cleaned with 0.5% hydrogen peroxide solution before sterilization.
2. Water quality monitoring must be strict. Check the conductivity (should be<2 μ S/cm), pH value (5.0-7.0), and temperature (cyclic insulation above 72 ℃) every 2 hours. Conduct comprehensive inspections of storage tanks and main water supply/return ports on a weekly basis, and inspect each usage point on a monthly basis to ensure compliance with pharmacopoeia standards.
3. The replacement of vulnerable parts needs to be carried out according to the plan. The respirator filter should be replaced every six months, the TOC monitor UV lamp should be replaced every six months, and the suction water pump head should be replaced every year. Regularly inspect pumps, valves, pipelines, and other components, and replace worn or aging parts in a timely manner.
4. Attention should also be paid to the operating environment of the equipment. The storage tank should be installed in a ventilated, dry, and suitable temperature location, avoiding direct sunlight and high temperature and humidity, and keeping the surrounding area clean. Special attention should be paid to antifreeze and insulation in winter, and residual liquids should be drained to avoid material brittleness.