Freeze dryer (freeze dryer)It is a technology that uses the principle of sublimation for drying, which involves rapidly freezing the dried substance at low temperatures, and then directly sublimating the frozen water molecules into water vapor under appropriate vacuum conditions to escape The product obtained from freeze-drying is called Lyophilizer, and this process is called Lyophilization.
The substance is always at a low temperature (frozen state) before drying, and ice crystals are evenly distributed in the substance. During the sublimation process, concentration will not occur due to dehydration, and side effects such as foam and oxidation caused by water vapor are avoided. The dry substance is in the form of a dry sponge with multiple pores, and its volume remains basically unchanged. It is highly soluble in water and can be restored to its original state. To prevent the physical, chemical, and biological denaturation of dry substances to a large extent.
The freeze-drying machine system consists of a refrigeration system, a vacuum system, a heating system, and an electrical instrument control system. The main components of a freeze-drying machine include a drying oven, condenser, refrigeration unit, vacuum pump, heating/cooling device, etc. The working principle of a freeze dryer is to first freeze the dried item below the triple point temperature, and then under vacuum conditions, the solid water (ice) in the item is directly sublimated into water vapor, which is removed from the item to dry it. After pre-treatment, the materials are sent to the quick freezing warehouse for freezing, then sent to the drying warehouse for sublimation and dehydration, and finally packaged in the post-processing workshop. The vacuum system establishes low-pressure conditions for the sublimation drying chamber, the heating system provides sublimation latent heat to the material, and the refrigeration system provides the required cooling capacity to the cold trap and drying chamber.
This device adopts efficient radiation heating, ensuring uniform heating of materials; Adopting an efficient water trap and capable of achieving rapid defrosting; Adopting an efficient vacuum unit and capable of achieving oil-water separation; Adopting a parallel centralized refrigeration system, with multiple on-demand cooling channels, stable operating conditions, and favorable energy-saving benefits; Adopting artificial intelligence control, with high control accuracy and easy operation.
The quality requirements for freeze-dried products are: unchanged biological activity, uniform appearance and color, full shape, firm structure, fast dissolution rate, and low residual moisture. To obtain high-quality products, one should have a comprehensive understanding of the theory and process of freeze-drying. The freeze-drying process includes three stages: pre freezing, sublimation, and re freeze-drying. Reasonably and effectively shortening the freeze-drying cycle has significant economic value in industrial production.