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Structure and principle of liposome extruder
Date: 2024-04-25Read: 7
Liposome extruder is a device used for preparing liposomes, which can extrude phospholipids and other components under high pressure to produce spherical or elliptical liposomes. Liposome extruder is a device that facilitates small-scale preparation of liposomes. Today, the editor will take you to understand the structure and principle of liposome extruder.
The liposome extruder consists of the following parts:
1. Pressure generator: used to generate high pressure, extrude phospholipids and other components, and form liposomes.
2. Phospholipid solution injection device: Inject phospholipid solution and other components into a pressure generator.
3. Liposome extruder: a device that extrudes phospholipid solutions under high pressure to form liposomes.
4. Aggregator: used to collect generated liposomes.
5. Control system: receives user instructions and controls the operation of equipment.
The liposome extruder breaks down the bilayer structure of phospholipids through high-pressure extrusion to form a single-layer liposome. The main preparation principle is as follows:
1. Dissolve phospholipids and other components in an appropriate solvent to prepare a phospholipid solution.
2. Input the prepared phospholipid solution into the extrusion chamber.
3. Under high pressure, phospholipids and other components are extruded to form liposomes.
4. Remove the generated liposomes from the aggregator and perform further processing.