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Shanghai Tianhe Pharmaceutical Machinery Co., Ltd
Shanghai Tianhe Pharmaceutical Rotary Granulator: Practical Equipment for Pharmaceutical Particle Production
Date: 2025-09-08Read: 2
In the production of granules in the pharmaceutical industry, the granulation accuracy, efficiency, and hygiene standards of equipment directly affect the quality of drugs. The rotary granulator developed by Shanghai Tianhe Pharmaceutical is designed to meet the requirements of pharmaceutical processes. Through stable rotary granulation technology, it achieves the conversion of powder materials into uniform particles, becoming a commonly used equipment for the production of traditional Chinese medicine and chemical medicine particles, providing reliable particle forming solutions for pharmaceutical companies.
1、 Core granulation principle: adapted to pharmaceutical process requirements
The Shanghai Tianhe Pharmaceutical rotary granulator adopts the integrated principle of "extrusion granulation", which meets the requirements of the pharmaceutical industry for particle uniformity and stability. When the equipment is working, the pre processed powder materials (such as traditional Chinese medicine extract powder and chemical powder) enter the granulation chamber through the feeding hopper. The rotating pressure wheel in the granulation chamber squeezes the materials to the surface of the sieve. Under the action of centrifugal force and extrusion force, the materials pass through the sieve holes to form cylindrical particles, which are then cut by a cutting knife to a set length to form uniformly sized particles.
This granulation method can adjust the particle size by replacing different mesh screens (usually 20-60 mesh) to meet the production needs of different dosage forms (such as granules, capsule filled granules), and the material does not generate excessive heat during the granulation process, which can better preserve the active ingredients of the drug and meet the protection requirements of pharmaceutical processes for material activity.
2、 Key design feature: Ensuring granulation quality and safety
1. Sanitary grade structure, in compliance with GMP standards
The components that come into contact with the equipment and materials, such as the granulation chamber, pressure wheel, and screen mesh, are made of 316L stainless steel and have undergone mirror polishing treatment on the surface (roughness Ra ≤ 0.8 μ m). There are no cleaning dead corners, which can effectively prevent material residue and bacterial growth; The granulation room adopts a quick opening design, which is easy to disassemble, clean and sterilize, in compliance with the GMP standards of the pharmaceutical industry, and ensures the hygiene and safety of the drug production process.
2. Intelligent control enhances operational convenience
Equipped with a touch control panel, it can intuitively set parameters such as granulation speed, feeding speed, cutting length, etc., and display production data in real time (such as particle yield and running time); The system supports parameter storage function, which can save multiple sets of production formulas. When changing products, there is no need for repeated debugging, reducing the operating threshold and minimizing the impact of human error on granulation quality.
3. Stable operation to reduce the risk of malfunctions
Adopting a high-precision transmission system, the gap between the pressure wheel and the screen mesh can be precisely controlled through an adjusting mechanism to ensure uniform material extrusion force and avoid particles being too loose or too hard; The equipment is equipped with an overload protection device. When there is too much material in the granulation room or foreign objects get stuck, the motor automatically stops and alarms to prevent component damage and extend the service life of the equipment.
3、 Applicable scenarios
1. Adapt to the multi scenario needs of the pharmaceutical industry
Widely used in the production of traditional Chinese medicine granules (such as cold clearing granules and Banlangen granules), the preparation of chemical medicine granules (such as antibiotic granules and vitamin granules), and the processing of health product granules (such as protein powder granules and probiotic granules). Both dry granulation (direct powder granulation) and wet granulation (granulation with adhesive materials) can operate stably and adapt to different material characteristics.
The Shanghai Tianhe Pharmaceutical rotary granulator meets the core requirements of granule production in the pharmaceutical industry with the characteristics of "uniform granulation, hygiene and safety, and convenient operation". It can improve production efficiency and ensure drug quality, and is a highly practical key equipment in the granule production line of pharmaceutical enterprises.