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Suzhou Aitson Pharmaceutical Equipment Co., Ltd

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Process principle of experimental rotary sterilization cabinet
Date: 2025-07-14Read: 7
The experimental rotary sterilization cabinet is a sterilization equipment designed specifically for laboratories and small batch production. Its core working principle combines wet heat sterilization with mechanical rotation technology, achieving efficient sterilization effects through precise control of temperature, pressure, and rotation parameters.
1、 Working principle: Rotation and wet heat synergistic effect
1. Fundamentals of Damp Heat Sterilization
The equipment heats clean water with boiler steam to form supersaturated steam (not directly using boiler steam), which releases heat energy under pressure loss conditions in the sterilization room, causing microbial proteins to denature and die. The sterilization temperature is usually controlled at around 121 ℃, and the sterilization time is adjusted according to the characteristics of the material.
2. Functional design of rotating system
Dynamic uniform heating: The rotating frame drives the sample to continuously flip at a preset speed (adjustable), avoiding sedimentation and layering, ensuring that heat penetrates to the center of the container, and significantly improving sterilization uniformity.
Heat exchange acceleration: Rotation promotes the contact efficiency between the sterilization medium (steam or superheated water) and the sample surface, shortens the heating/cooling time, and is suitable for thermosensitive materials.
3. Automated program control
The equipment operation covers the entire process of 'water injection → shaking → heating → sterilization → cooling'. The PLC system automatically regulates the rotation speed, temperature, and pressure, and supports parameter storage and traceability to meet the requirements of experimental repeatability.
2、 Core advantage: Experimental level precision and adaptability
1. Sterilization uniformity guarantee
Rotating design solves the common temperature stratification problem in static sterilization. Experimental data shows that the temperature difference inside the cabinet can be controlled within ± 1 ℃, especially suitable for viscous liquids or samples containing particles.
2. Thermal sensitive material protection
Rapid temperature rise and fall capability (such as cooling stage water circulation system) reduces heat exposure time, prevents protein denaturation or crystallization, and is suitable for vaccines, biologics, etc.
3. Multi functional adaptive design
Support loading of various containers such as ampoules, culture dishes, fabrics, etc;
Optional vacuum leak detection function, using rotation process to detect packaging sealing.