The medicinal dry granulation machine is a process of pouring mixed dry powder materials (Western medicine or traditional Chinese medicine extracts) into a conical hopper. Due to the presence of a certain amount of crystal water in the particles, the material is compressed and degassed by the downward rotation of an irregular conical screw to generate pre pressure, which is then crushed into flakes and sent to the granulation system for granulation.

Powder raw materials extracted from western medicine or traditional Chinese medicine (spray drying, freeze drying) are characterized by different particle sizes, uneven density, poor liquidity and easy layering. Therefore, to solve the characteristics of these materials, a key processing step - granulation - must be passed through in order to smoothly proceed to the next process: ⑴ tablet pressing ⑵ capsule filling ⑶ granule packaging.

Let's take a look at the future development trends of pharmaceutical dry granulation machines together!

Currently, using dry granulation mechanism to solve the above problems is a mainstream trend,
This method utilizes the crystallization water of the material itself and relies on the principle of mechanical extrusion to directly compress, shape, roughly crush, and granulate the raw material powder. It is an energy-saving and energy-saving method that can continuously granulate, with simple and convenient operation and low production costs.
Dry granulation requires less equipment, lower maintenance costs, occupies less space, and has lower production and processing costs compared to wet granulation.
Dry granulation has a simpler processing technology compared to wet granulation, thus reducing the need for GMP certification.
Compared to wet granulation, the advantage of dry granulation is still low energy consumption; Granulation does not require the addition of any additives or adhesives; After granulation, the product has uniform particle size, high packing density, and good flowability. It is easy to store and transport after granulation, with flying dust and less waste; Easy to control solubility, porosity, and specific surface area; Especially for some drugs that cannot be dissolved in water or alcohol, as well as antibiotics and drugs with strong heat sensitivity that are afraid of heating, traditional Chinese medicine extracts that do not meet the required weight ratio, and cannot add adhesives or excipients, they must be processed through dry granulation technology.

The entire machine is easy and convenient to disassemble and clean. The sealing structure inside and outside the hood is designed reasonably, and the electrical box and transmission parts are waterproof. There is no need to worry about pollution and damage to electrical appliances and equipment during the cleaning process.

The above are the advantages and future development trends of medicinal dry granulation machines. We hope it will be helpful for you when using dry granulation machines.