1、 Technical principles and core structure

The wet granulation machine forcibly stirs the powder material with a binder (such as water, ethanol, or polymer solution) in a mixing container to form a uniform wet state, and then squeezes it into granules. Its core components include:

1. High speed mixing blade: using variable frequency speed regulation technology (speed range 50-1500rpm) to achieve three-dimensional mixing of materials;

2. Cutting blade system: equipped with double-layer irregular blades, the particle size control accuracy can reach ± 0.3mm;

3. Drying module: Integrated fluidized bed or microwave drying device, increasing water evaporation efficiency by more than 40%.

2、 Key applications in pharmaceutical processes

1. Solid preparation production

Covering over 80% of dosage forms such as tablets, capsules, and granules, precise preparation of multi-layer coated particles can be achieved in the field of controlled release formulations. The application case of a certain sustained-release tablet production line shows that the particle angle of repose has been optimized from 52 ° to 32 °, and the pass rate of tablet pressing has been increased to 99.6%.

2. Expansion of the food industry

Used for granulation processing of instant coffee, seasoning and other products, by adjusting the adhesive ratio (recommended 10-25% ethanol concentration), the product dissolution rate can be increased by up to 30%.

3. Preparation of new chemical materials

In the molding of catalyst carriers, molecular sieves and other materials, microporous structured granulation with sphericity>0.9 is achieved, with a specific surface area retention rate of over 95%.