The dissolution automatic sampling system is fully compatible with most manufacturers' dissolution instruments. Upgradeable WiFi, RS232, RS485, LAN, Bluetooth data interfaces. The entire series uses a 26ml high-precision syringe as the sampling power. Fast sampling speed and high accuracy. The entire system has the functions of initial filtrate and distribution, and can realize the disposal of initial filtrate and the distribution and retention of subsequent filtrate. And the samples can be collected directly into ampoules. Adopting 8/12 precision injection pumps to achieve high-precision automatic filtration, sampling, and fluid replenishment, with advanced structure, accurate control, and high degree of intelligence.
The daily use precautions of the dissolution automatic sampling system can be divided into four aspects: preparation before operation, experimental process management, maintenance and safety standards. The following are specific points:
1、 Preparation before operation
1. Equipment inspection and cleaning
Before use, it is necessary to check whether the dissolution apparatus, sampler, rotating rod and other components are in good condition to ensure that there is no damage or contamination.
Clean and disinfect the instrument to avoid cross contamination, and pay special attention to rinsing the pipeline residue with purified water.
2. Parameter calibration and environmental settings
Calibrate the temperature probe (error ≤ 1 ℃), speed, and sampling time to ensure that the water level in the water bath meets the standard and the temperature is stable (usually 37 ± 0.5 ℃).
The instrument should be placed on a vibration free, horizontally stable table to avoid external interference.
2、 Experimental process management
1. Sampling operation specifications
The sampling needle needs to be equipped with a 10 μ m filter head, and the sampling time should be controlled within 1 minute. The filtrate needs to be filtered and data recorded within 30 seconds.
• Avoid mechanical vibration or air entering the sampling tube to prevent sample stratification or bubbles from affecting the results.
2. Real time monitoring
Observe the water circulation, temperature stability, and rotational speed, and immediately shut down for troubleshooting in case of abnormal situations.
3、 Maintenance and upkeep
1. Regular maintenance
Replace the purified water in the water bath every half month, replace the air filter head and lubricate the guide rod every six months, and replace the worn drive belt in a timely manner.
After the experiment, the outer wall of the sampling needle, paddle rod, and dissolution cup need to be cleaned, and any residual acidic medium needs to be treated immediately to prevent corrosion.
2. Pipeline and sensor maintenance
Regularly check the weighing sensor and liquid level sensor to ensure proper fluid replenishment/cleaning function.
4、 Safety precautions
1. Protective measures
Wear protective clothing, gloves, and goggles when configuring acidic solvents, and replace damaged pipelines immediately.
2. Prohibited operation
Do not start the heating function without water or use organic solvents to clean the casing.