Rc-6 dissolution testerComposed of a box body, control system, electrical system, water bath system, transmission system, sensors, paddle components, basket components, etc., a precision control system composed of a single-chip microcomputer is used to centrally control each component; The instrument has a high degree of automation, high control accuracy, high sensitivity, small error, low noise, and easy operation.

RC-6 dissolution tester is used to simulate the human body for the determination of drug dissolution in tablets, granules, and capsules. It can also be applied in the food and cosmetics industry for necessary dissolution testing.

Working principle of rc-6 dissolution tester: The host adopts a mechanical structure of dual column lifting transmission, which has a beautiful appearance and stable and reliable working performance. The circuit part adopts a novel circuit design, and the clock control module adopts an advanced program preset chip. During the experiment, single position time control and multi-stage time reminder programs can be preset. The automation program is high, the operation is convenient, the performance is *, and the test data accuracy is high.

Rc-6 dissolution testerUsing standard operating procedures

1. Place the dissolution cup into the six holes of the instrument, adjust its position with a concentric ring cover, and then fix it with a positioning piece.

2. Select the basket or slurry according to the quality standards, adjust the distance between the basket or slurry and the bottom of the dissolution cup using positioning rods, and then tighten the knob to fix the basket or slurry.

3. Add the specified amount of solvent to the dissolution cup, and then fill the water bath box with water to the waterline position.

4. Plug in the power socket, turn on the power switch, and preset the specified speed, dissolution time, sampling interval time, and water temperature control parameters through the buttons on the control panel.

5. When the temperature of the solvent in the cup reaches a constant temperature of 37 ± 0.5 ℃ through a water bath, put 6 pieces (granules) of the test sample into six rotating baskets or directly into each rotor cup, lower the rotating basket or rotor into the container, select the "Run" button of the intelligent dissolution instrument to start immediately and start timing, cover with organic glass cover, and insert the sampling needle into the outer hole.

6. When the intelligent dissolution instrument beeps at the specified dissolution time, an appropriate amount of solution is taken from the designated sampling point (at a distance of 10mm from the top of the basket or blade to the middle of the liquid surface and the beaker wall), filtered through a 0.8um microporous membrane, and injected into a test tube.

7. After completing the sampling, turn off the power switch, unplug the power plug, lift the basket or slurry, remove the basket body, pour out the solution in the cup, clean all utensils, invert and dry for later use.

　　Rc-6 dissolution testerPrecautions

1. When using the basket rotation method for measurement, the swing amplitude during basket rotation should not exceed ± 1.0mm.

2. The entire device of the intelligent dissolution instrument should remain stable and not shake or swing when the instrument motor is running.

3. During operation, the water temperature of the water bath should be controlled at 37 ± 0.5 ℃.

4. When extracting the solution, the process from sampling to filtration should be completed within 30 seconds.

That's allRc-6 dissolution testerThe principle and usage introduction, I hope it is helpful to everyone!