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Wuxi Zhanghua Pharmaceutical Equipment Co., Ltd

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    zqz008@126.com

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    13961802200

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    Shitangwan Industrial Park (Doumen), Huishan District, Wuxi City, Jiangsu Province

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The main structural components of the three in one filtration, washing, and drying production line
Date: 2025-05-28Read: 5
The filtration, washing, and drying three in one production line is a highly integrated system that requires supporting auxiliary equipment in addition to the core three in one host to achieve a complete production process. The following is the complete system composition carefully crafted by Wuxi Zhanghua Pharmaceutical Equipment Co., Ltd. for you, including the host, supporting equipment, and functional specifications:
  1、 Core host device (three in one host)
Filter, Wash and Dry Integrated Machine
Tank system: Wuxi Zhanghua Pharmaceutical uses high-quality 316L stainless steel/Hastelloy to create a pressure resistant closed container, equipped with jacket heating/cooling function to ensure stable processing of materials at suitable temperatures.
Filter unit: The bottom adopts a metal sintered filter plate (or filter cloth), which supports positive pressure/vacuum filtration and can efficiently separate solid-liquid phases to meet the filtration needs of different materials.
Mixing system: Hollow shaft heating combined with adjustable propeller blades, with forward and reverse rotation functions, ensures uniform mixing of materials, efficient heating and mass transfer, especially suitable for processing high viscosity materials.
Spray washing: Spray balls are installed on the top/side to achieve multi-level solvent distribution, wash materials from multiple directions, improve washing efficiency, and reduce impurity content.
Drying system: combining vacuum drying with jacket/stirring shaft thermal conductivity, or using hot nitrogen circulation, to achieve fast and uniform drying, especially friendly to heat sensitive materials, ensuring product quality.
Unloading device: equipped with pneumatic discharge valve (or screw conveyor), convenient discharge, flexible selection according to material characteristics, ensuring production continuity.


  2、 Supporting auxiliary equipment
1. Pre processing equipment (upstream supporting)
Reaction kettle/crystallization tank: The designed reaction kettle/crystallization tank can be used for material synthesis or crystallization, with precise control of reaction conditions, forming an ideal suspension and stably transporting it to the three in one host, laying a good foundation for subsequent processing.
Conveyor pump: Select suitable screw pumps, diaphragm pumps, etc. to smoothly and efficiently pump the reaction solution or crystallization solution into the three in one host, ensuring smooth material transfer and avoiding blockage and leakage.
2. Filtering power system
Vacuum pump: Provides multiple options such as Roots vacuum pump and water ring pump to provide sufficient negative pressure filtration power for the filtration process. Paired with a vacuum buffer tank, it stabilizes the filtration pressure and improves filtration efficiency and quality.
Air compressor/nitrogen compressor: Supply the pressure required for positive pressure filtration, while also providing inert gas protection to meet explosion-proof requirements, ensuring safe and reliable production processes, especially suitable for handling flammable and explosive materials.
3. Washing system
Solvent storage tank: used to store various types of washing liquids (such as water, ethanol, acetone), equipped with heating/cooling functions according to demand, to ensure the appropriate temperature of the washing liquid, improve the washing effect, and optimize product quality.
Metering pump: High precision gear pumps, plunger pumps, etc. are used to accurately control the amount of detergent used, achieve precise washing, avoid solvent waste, and reduce production costs.
4. Drying system
Condenser: Choose a tubular condenser to efficiently condense and recover volatile solvents, reduce solvent loss, minimize environmental pollution, and improve production efficiency.
Condensed liquid receiving tank: Collect the condensed solvent, which can be treated and refluxed to the solvent storage tank to achieve solvent recycling and create a green production mode.
Hot air circulation system (optional): including heater, fan, and filter, used for hot air drying, precise control of drying temperature and air volume, further improving drying efficiency and quality stability.
5. Post processing equipment (downstream supporting)
Crusher: If the material clumps after drying, an air flow crusher can be used for crushing to restore good flowability of the material, meet subsequent process requirements, and ensure product performance.
Screening machine: Control the particle size of the finished product through equipment such as vibrating screens to ensure uniform particle size and meet quality standards and customer customization requirements.
Packaging system: equipped with automatic weighing and packaging equipment, adopting dust-proof design, achieving precise and efficient packaging of finished products, enhancing product added value, and facilitating storage and transportation.
6. Control system
PLC/DCS system: integrates various sensors (temperature, pressure, pH, etc.) to achieve automated control processes, accurately monitors production parameters, ensures stable production operation, reduces manual intervention, and improves production efficiency and product quality consistency.
CIP/SIP system: Essential for the pharmaceutical industry, meeting online cleaning/sterilization needs, ensuring equipment cleanliness and hygiene, complying with drug production quality management standards, and ensuring drug safety.
7. Environmental protection and safety equipment
Waste gas treatment device: using technologies such as activated carbon adsorption or condensation recovery, effectively treating organic waste gas, reducing emission pollution, maintaining workshop environment, ensuring employee health, and assisting enterprises in environmental compliance.
Explosion proof system: For the handling of flammable and explosive materials, explosion-proof equipment such as explosion-proof motors and nitrogen protection are installed to ensure the safety of the production process from multiple perspectives, reduce safety risks, and ensure worry free production.
Wastewater treatment unit: Treat washing waste liquid, equipped with neutralization tanks, membrane filtration and other facilities, achieve standard discharge of wastewater, reduce environmental pressure, shape the environmental image of the enterprise, and promote sustainable development.
  
  3、 Typical Process Flow Supporting Diagram
[Reactor] → → [Three in One Host]
↓
← [Condenser] ← [Drying Waste Gas]
↓
[Solvent Recovery Tank] ←
↓
[Crusher] → →

  4、 Key selection points
Material characteristic matching
Corrosive materials: We offer corrosion-resistant materials such as Hastelloy or PTFE lining to ensure the service life of equipment and avoid material contamination and equipment damage.
Thermally sensitive materials: Vacuum drying combined with low-temperature condensation scheme is preferred to accurately control the drying temperature, prevent material denaturation due to high temperature, and ensure product quality and activity.
Capacity demand
Small scale testing line: The main unit has a capacity of 50-500L and is equipped with a micro vacuum pump to meet the needs of small-scale production such as scientific research and small-scale testing, reduce investment costs, and facilitate process exploration and optimization.
Industrial grade production line: The main engine has a capacity of 1-10m ³ and is equipped with a multi-stage vacuum system to efficiently handle large-scale production tasks, ensure production capacity output, help enterprises expand production scale, and enhance market competitiveness.
industry standards
Pharmaceutical industry: Strictly comply with GMP standards, equip production lines with complete CIP/SIP and verification documents, ensure equipment cleanliness and sterility, guarantee drug quality and safety, and assist enterprises in passing drug regulatory audits.
Chemical industry: Focus on explosion prevention and waste gas treatment, customize explosion prevention plans based on the characteristics and process requirements of chemical materials, equip with efficient waste gas treatment systems, achieve safe production and environmental emissions, and comply with strict safety and environmental protection standards in the chemical industry.
  5、 Common configuration schemes
Pharmaceutical aseptic raw material production line: three in one host+aseptic reaction kettle+low-temperature condenser+CIP/SIP+isolator packaging, ensuring all-round aseptic production of drugs, meeting strict quality control requirements, suitable for high value-added aseptic raw material production, improving drug quality and market competitiveness.
Chemical high-purity material production line: three in one host+explosion-proof nitrogen system+solvent recovery tower+airflow crusher, ensuring safe and efficient chemical production, high solvent recovery utilization rate, uniform particle size of finished products, meeting the production needs of high-purity materials in the chemical industry, and helping chemical enterprises produce refined and high-end products.
Wuxi Zhanghua Pharmaceutical Equipment Co., Ltd. focuses on providing customized filtration, washing, and drying three in one production line technology solutions for customers. We accurately select matching materials based on customer needs, material characteristics, and process requirements to ensure that the production line is compatible with the production process, achieving fully enclosed and automated production from feeding to finished products, significantly improving production efficiency, reducing pollution risks, and helping enterprises move towards new heights of intelligent and green production.