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E-mail
3495811982@qq.com
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Phone
13619217766
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Address
No. 3 Xingzhong Road, Lianhu District, Xi'an, China
Xi'an Kaixin Biotechnology Co., Ltd
3495811982@qq.com
13619217766
No. 3 Xingzhong Road, Lianhu District, Xi'an, China
MPEG Thiolactote is a monofunctionalized polyethylene glycol (PEG) derivative, consisting of a methoxy end, a polyethylene glycol chain, and a thiolactate end. This compound can form thiol groups (- SH) through ring opening under mild conditions. Thiol groups have high reactivity and can covalently bind with molecules such as gold nanoparticles and proteins, achieving biological coupling or chemical modification. Its good water solubility and biocompatibility make it widely used in protein modification (such as PEGylation), drug delivery systems (such as nanocarrier functionalization), and surface modification of biomaterials. During storage, avoid exposure to light and moisture, and maintain a low temperature and dry environment.
Chinese name: Methoxypolyethylene glycol thiolactate ester
English name: mPEG Thiolactote; Methoxy-PEG-SS-Octadecanol
分子量: 0.4k,0.6k,1k,2k,3.4k,5k,10k 等(支持定制)
Supplier: Xi'an Kaixin Biotechnology Co., Ltd
Purity: ≥ 95%
Appearance: Solid powder or granules
Solubility: soluble in some organic solvents and water
Storage conditions: Freeze and dry below -20 ℃ to avoid repeated freeze-thaw cycles
Packaging specifications: 1g, 5g, 10g
Security protection:
During the operation, disposable protective clothing, masks and other protective equipment should be worn to ensure self safety.
This reagentonly useIn scientific research
【 Application Fields 】
Based on its mild and efficient coupling ability, it is mainly used for:
PEGylation modification of proteins/peptides: Site directed modification of primary amino groups under physiological conditions to improve the pharmacokinetic properties of drugs and reduce immunogenicity.
Functional nanocarrier construction: used to modify liposomes, polymer nanoparticles, etc., by introducing a PEG "invisible" layer and endowing the surface with further reactive thiol groups.
Material surface modification: Introducing thiol groups onto the surface of metal nanoparticles or polymer materials to achieve stable functionalization.
Polymer synthesis: as an organic intermediate, used to prepare more complex functional polymer materials
【 Related reagents 】
PLL-HAPLL-HA, Polylysine hyaluronic acid
PLGA-COOH poly (propylene glycol) - carboxyl group
PLGA-NH2 poly (lactic acid hydroxy acetic acid) amino
PLGA-OH poly (D, L-lactic acid co glycolic acid) - hydroxy
PLGA Thiol Poly (Lactide Ethide) - Thiol
PLGA-COOH Poly (Lactic Acid Hydroxyacetic Acid) Carboxyl
PLL-PEG-FolatePLL-PEG-FA / PLL-PEG-FA
Plg-eg-shplg-skj / plg-eg-sheg-sh
PLLA-NH2 polylactic acid (L -) - amino PLLA-NH2
Plys-PEG-NHSPlys-PEG-NHS / Plys-PEG-NHS
PPHE-PEG-OHPPHE-PEG-OH / PPHE-PEG-OH
Poly(D,L-lactide-co-glycolide)-Acid 羟基化PLGA
PLGA-PEI poly (D, L-lactic acid co glycolic acid) - b-polyethyleneimine
More PEG SheetMore PEG Sheet / More PEG Sheet
PLL-PEG-MAL, Mal PEG PLL Polylysine Block Functionalized Polymer
The above content is edited and organized by YNN of Xi'an Kaixin Biotechnology Co., Ltd
This reagent is only used for scientific research experiments and cannot be used on the human body