Welcome Customer !

Membership

Help

Xi'an Kaixin Biotechnology Co., Ltd
Custom manufacturer

Main Products:

pharmamach>Download Materials>Introduction to the Core Information of Methoxy PEG SS Octadecanol, a Monofunctionalized PEG Derivative
Download

Xi'an Kaixin Biotechnology Co., Ltd

  • E-mail

    3495811982@qq.com

  • Phone

    13619217766

  • Address

    No. 3 Xingzhong Road, Lianhu District, Xi'an, China

Contact Now
Introduction to the Core Information of Methoxy PEG SS Octadecanol, a Monofunctionalized PEG Derivative
Date: 2025-12-31Read: 0

MPEG Thiolactote is a monofunctionalized polyethylene glycol (PEG) derivative, consisting of a methoxy end, a polyethylene glycol chain, and a thiolactate end. This compound can form thiol groups (- SH) through ring opening under mild conditions. Thiol groups have high reactivity and can covalently bind with molecules such as gold nanoparticles and proteins, achieving biological coupling or chemical modification. Its good water solubility and biocompatibility make it widely used in protein modification (such as PEGylation), drug delivery systems (such as nanocarrier functionalization), and surface modification of biomaterials. During storage, avoid exposure to light and moisture, and maintain a low temperature and dry environment.

Chinese name: Methoxypolyethylene glycol thiolactate ester

English name: mPEG Thiolactote; Methoxy-PEG-SS-Octadecanol

分子量: 0.4k,0.6k,1k,2k,3.4k,5k,10k 等(支持定制)

Supplier: Xi'an Kaixin Biotechnology Co., Ltd

Purity: ≥ 95%

Appearance: Solid powder or granules

Solubility: soluble in some organic solvents and water

Storage conditions: Freeze and dry below -20 ℃ to avoid repeated freeze-thaw cycles

Packaging specifications: 1g, 5g, 10g

Security protection:

During the operation, disposable protective clothing, masks and other protective equipment should be worn to ensure self safety.

This reagentonly useIn scientific research

【 Application Fields 】

Based on its mild and efficient coupling ability, it is mainly used for:

PEGylation modification of proteins/peptides: Site directed modification of primary amino groups under physiological conditions to improve the pharmacokinetic properties of drugs and reduce immunogenicity.

Functional nanocarrier construction: used to modify liposomes, polymer nanoparticles, etc., by introducing a PEG "invisible" layer and endowing the surface with further reactive thiol groups.

Material surface modification: Introducing thiol groups onto the surface of metal nanoparticles or polymer materials to achieve stable functionalization.

Polymer synthesis: as an organic intermediate, used to prepare more complex functional polymer materials

【 Related reagents 】

PLL-HAPLL-HA, Polylysine hyaluronic acid

PLGA-COOH poly (propylene glycol) - carboxyl group

PLGA-NH2 poly (lactic acid hydroxy acetic acid) amino

PLGA-OH poly (D, L-lactic acid co glycolic acid) - hydroxy

PLGA Thiol Poly (Lactide Ethide) - Thiol

PLGA-COOH Poly (Lactic Acid Hydroxyacetic Acid) Carboxyl

PLL-PEG-FolatePLL-PEG-FA / PLL-PEG-FA

Plg-eg-shplg-skj / plg-eg-sheg-sh

PLLA-NH2 polylactic acid (L -) - amino PLLA-NH2

Plys-PEG-NHSPlys-PEG-NHS / Plys-PEG-NHS

PPHE-PEG-OHPPHE-PEG-OH / PPHE-PEG-OH

Poly(D,L-lactide-co-glycolide)-Acid 羟基化PLGA

PLGA-PEI poly (D, L-lactic acid co glycolic acid) - b-polyethyleneimine

More PEG SheetMore PEG Sheet / More PEG Sheet

PLL-PEG-MAL, Mal PEG PLL Polylysine Block Functionalized Polymer

The above content is edited and organized by YNN of Xi'an Kaixin Biotechnology Co., Ltd

This reagent is only used for scientific research experiments and cannot be used on the human body