MA PEG Poly Ornithines (Methacrylate Polyethylene Glycol Polyornithine) is a multifunctional block copolymer

It is a linear block copolymer composed of three functional modules:

Methacrylate (MA) end group: Provides polymerizable double bonds, facilitating further crosslinking or functionalization of materials through free radical polymerization or click chemistry.

Polyethylene glycol (PEG) segments: can improve water solubility, reduce immune recognition, and prolong the time of drugs in the bloodstream.

Poly Ornithine segment: composed of positively charged poly (L-ornithine), it is the functional core that can form complexes with negatively charged nucleic acids (such as DNA, siRNA) or proteins through electrostatic interactions, and promote cell membrane adsorption and endocytosis

Chinese name: Methacrylate Polyethylene Glycol Polyornithine

English name: MA-PEG-Poly-Ornitine; Methacrylate-PEG-Poly-Ornithines

分子量： 0.4k，0.6k，1k，2k，3.4k，5k，10k 等（支持定制）

Purity: ≥ 95%

Appearance: Solid powder or granules

Solubility: soluble in some organic solvents and water

Storage conditions: Freeze and dry below -20 ℃ to avoid repeated freeze-thaw cycles

Packaging specifications: 1g, 5g, 10g

Security protection:

During the operation, disposable protective clothing, masks and other protective equipment should be worn to ensure self safety.

This reagentonly useIn scientific research

【 Application Fields 】

Gene delivery: As a non viral vector, MA PEG Poly Ornithines compresses nucleic acids through charge interactions, forming nanoparticles that protect nucleic acids from enzymatic hydrolysis and promote cellular uptake and gene expression. The introduction of MA groups further achieves targeted modification of the carrier and improves delivery efficiency.

Cell culture: The MA PEG Poly Arnines coating can significantly improve cell adhesion and growth, especially suitable for cell types such as neurons and stem cells that are sensitive to surface properties. Combined with laminin, fibronectin, and other proteins, it can further enhance cell differentiation function.

Targeted therapy: By covalently binding MA groups to targeted molecules (such as antibodies and peptides), MA PEG Poly Ornithines can achieve targeted delivery of drugs or genes, reduce off target effects, and improve therapeutic efficacy.

Biomaterials modification: MA PEG Poly Ornithines can be used to modify the surface of biomaterials, improve their biocompatibility and functionalization, such as for tissue engineering scaffolds, implant coatings, etc.

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The above content is edited and organized by YNN of Xi'an Kaixin Biotechnology Co., Ltd

This reagent is only used for scientific research experiments and cannot be used on the human body