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Newcomer savior! MP-MPEG's "foolproof operation manual" parameters/applications/advantages (one step at a time)
Date: 2025-12-29Read: 0

Methoxy PEG MP (monophosphate methoxy polyethylene glycol) is a functionalized polyethylene glycol (PEG) derivative with important applications in biomaterials, drug delivery, and surface modification

Structural analysis: Its name can be broken down into three parts:

Methoxy: located at one end of the PEG chain, providing inert capping, enhancing hydrophilicity and biocompatibility.

PEG (polyethylene glycol): As a hydrophilic linking arm, it improves water solubility, prolongs circulation time, and reduces immunogenicity.

MP (monophosphate): Refers to a molecule with a phosphate group (- PO ∝ H ₂ or its salt form - PO ∝⁻) at the reactive end, which can be used for further coupling or modification

Chinese name: Monophosphate methoxy polyethylene glycol

English name: MP-MPEG, Methoxy PEG MP

Supplier: Xi'an Kaixin Biotechnology Co., Ltd

Purity: ≥ 95%

Appearance: Solid powder or granules

Solubility: soluble in some organic solvents and water

Storage conditions: Freeze and dry below -20 ℃ to avoid repeated freeze-thaw cycles

Packaging specifications: 1g, 5g, 10g

Security protection:

During the operation, disposable protective clothing, masks and other protective equipment should be worn to ensure self safety.

This reagent is limited to scientific research only

【 Application 】

Biomaterial modification: By coordinating or covalent interactions between phosphate groups and material surfaces (such as metal oxides and hydroxyapatite), the hydrophilicity, biocompatibility, and anti protein adsorption properties of the material are improved.

Surface modification: Used for medical device coatings to reduce non-specific adsorption and thrombus formation.

Biocoupling: As a connecting arm, it couples bioactive molecules (such as antibodies, ligands) onto nanoparticles or polymer carriers.

Advantages

Excellent biocompatibility: PEG chains provide low immunogenicity, and phosphate groups naturally exist in the body (such as ATP, DNA), reducing the risk of toxicity.

Functional diversity: Functional groups at both ends can react with different molecules to construct complex functional molecules.

Customizability: The molecular weight, functional group type, and reaction conditions can be flexibly adjusted to meet diverse needs

【 Related reagents 】

BOC-PEG folic acid

HO-PEG-MEAC

BOC-NH-PEG-FA

BOC-NH-PEG-Folate

HO-PEG-Methacrylate

BOC-NH-PEG-Folic acid

Hydroxyl-PEG-Methacrylate

Mannose PEG DSPE Phospholipid Polyethylene Glycol Mannose

ADH-HA-MAMA-HA-ADH ADH-HA-MA

HA-SS-PCLHA-SS-PCL, Hyaluronic acid disulfide bond polycaprolactone

HA-PEG-PLAHA-PEG-PLA, Hyaluronic acid polyethylene glycol polylactic acid

HYNIC-RDGHYNIC-RDG RDG-HYNIC Peptide Radioactive Label

Methyltetrazine-PEG-COOHMethyltetrazine-PEG-COOH

Methyltetrazine-PEG-BiotinMethyltetrazine-PEG-Biotin

Methyltetrazine-PEG-AlkyneMethyltetrazine-PEG-Alkyne

HO-PEG-HydrazideHO-PEG-Hydrazide / HO-PEG-Hydrazide

Methyltrazine-ICGMethyltrazine-ICG / Methyltrazine-ICG

Maleimide-PEG-PLGMaleimide-PEG-PLG / Mal-PEG-PLG

The above content is edited and organized by YNN of Xi'an Kaixin Biotechnology Co., Ltd

This reagent is only used for scientific research experiments and cannot be used on the human body