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Analysis of the structural formula of DBCO-PEG-NHS, phenyl cyclooctyl PEG active ester by Kaixin Biotechnology
Date: 2023-05-05Read: 0
English name: DBCO-PEG-NHS
Dibenzocyclooctyne-PEG-NHS
Chinese name: Diphenylcycloalkyne PEG active ester
Diphenylcycloalkyne polyethylene glycol active ester
Molecular weight: 10002000340050001000020000
Structural formula:
Kaixin Biotech DBCO-PEG-NHS structural formula
Appearance: White solid or semi-solid state may appear due to different molecular weights
Storage conditions: -20 ℃, away from light, dry.
Purpose: For scientific research experiments only, not for diagnosis and treatment
Caution: When using, be sure to dry and avoid frequent dissolution and freeze-drying.
English Introduction:
Dibenzocycolctyne (DBCO) PEG NHS derivatives can go Click Chemistry reaction without a need of any metal catalysts. The strain-promoted 1,3-dipolar cycloaddition of cyclooctynes and azides, also termed as the Cu-free click reaction, is a bioorthogonal reaction that enables the conjμgation of two molecules in aqueous solution. DBCO PEG derivatives possess fast kinetics and stability in aqueous buffer. DBCO reagents can be used to label azide-modified biomolecules spontaneous without the need for toxic Cu catalysts. PEGylation can increase solubility and stability and reduce immunogenicity of peptides and proteins. It can also suppress the non-specific binding of charged molecules to the modified surfaces.
Xi'an Kaixin Biotechnology Co., Ltd. is a domestic PEG supplier that can provide PEG derivatives with different molecular weights. The cyclic nodes of small molecule PEG can reach 1-36, and the molecular weights of high molecular weight PEG range from 1000-40000. The groups that can be modified include amino, NHBOC, Fmoc, carboxylic acid, Mal, NHS, azide, DBCO, Cy3/Cy5/Cy7, THP, benzyl, propynyl, brominated, tert butyl propionate, tert butyl acetate, methyl, biotin, pentafluorophenol, sulfonic acid ester, thiol, and the product purity is over 98%.
NHS ester-PEG-dibenzocycolctyne，MW 350
NHS-PEG-DBCO ，MW 350
Active ester polyethylene glycol diphenyl cyclooctylene, molecular weight 550
NHS ester-PEG-dibenzocycolctyne，MW 550
NHS-PEG-DBCO ，MW 550
Active ester polyethylene glycol diphenyl cyclooctylene, molecular weight 600
NHS ester-PEG-dibenzocycolctyne，MW 600
NHS-PEG-DBCO ，MW 600
Active ester polyethylene glycol diphenyl cyclooctylene, molecular weight 1000
NHS ester-PEG-dibenzocycolctyne，MW 1K
NHS-PEG-DBCO ，MW 1K
Active ester polyethylene glycol diphenyl cyclooctylene, molecular weight 2000
NHS ester-PEG-dibenzocycolctyne，MW 2K
NHS-PEG-DBCO ，MW 2K
Active ester polyethylene glycol diphenyl cyclooctylene, molecular weight 3400
NHS ester-PEG-dibenzocycolctyne，MW 3.4K
NHS-PEG-DBCO ，MW 3.4K
Active ester polyethylene glycol diphenyl cyclooctylene, molecular weight 5000
NHS ester-PEG-dibenzocycolctyne，MW 5K
NHS-PEG-DBCO ，MW 5K
Active ester polyethylene glycol diphenyl cyclooctylene, molecular weight 6000
NHS ester-PEG-dibenzocycolctyne，MW 6K
NHS-PEG-DBCO ，MW 6K
Active ester polyethylene glycol diphenyl cyclooctylene, molecular weight 10000
NHS ester-PEG-dibenzocycolctyne，MW 10K
NHS-PEG-DBCO ，MW 10K
Active ester polyethylene glycol diphenyl cyclooctylene, molecular weight 20000
NHS ester-PEG-dibenzocycolctyne，MW 20K
NHS-PEG-DBCO ，MW 20K
Active ester polyethylene glycol diphenyl cyclooctylene, molecular weight 30000
NHS ester-PEG-dibenzocycolctyne，MW 30K
NHS-PEG-DBCO ，MW 30K
Active ester polyethylene glycol diphenyl cyclooctylene, molecular weight 40000
NHS ester-PEG-dibenzocycolctyne，MW 40K
NHS-PEG-DBCO ，MW 40K
Active ester polyethylene glycol diphenyl cyclooctylene, molecular weight 800
NHS ester-PEG-dibenzocycolctyne，MW 800
NHS-PEG-DBCO ，MW 800
Active ester polyethylene glycol diphenyl cyclooctylene, molecular weight 3000
NHS ester-PEG-dibenzocycolctyne，MW 3K
NHS-PEG-DBCO ，MW 3K
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