toDry granulation machineAnalyze the characteristics of the manufacturing process

Zhangjiagang Aiguo Biotechnology Co., LtdDry granulation machineIt is a new equipment that uses the crystal water in the powder to directly degas, shrink, and pelletize the powder into ideal particles. The granulation process of a dry granulation machine does not require water, adhesives, or auxiliary agents, nor does it require subsequent drying. The granulation process does not experience high temperatures and is equipped with a water cooling device, which can process heat sensitive materials, moisture absorbing materials, or melting materials. The dry granulation machine can produce irregular small particles of (0.2-10 mm) or (80 mesh -8 mesh), as well as shaped particles of 4-50 mm (such as elliptical, flat circular, strip-shaped). The particles produced by the dry granulation mechanism can be directly packaged, or used as tablets, granules, capsules, etc.

The dry granulation machine has a novel and reasonable structure, stable and reliable performance, and easy cleaning and maintenance. The particles made from it can be used as tablet agents, granules, capsules, etc.Dry granulation machineMainly used for granulation in the manufacturing, food, chemical, and other industries. The dry granulation machine adopts electric hydraulic, simple and reliable operation, high degree of automation, and its operation process is sealed and pollution-free, which can meet the requirements of product hygiene. The dry granulation machine is particularly suitable for processing materials that cannot be added with water, adhesives, and auxiliary agents. The dry granulation machine can be fully automated for production, with easy operation. The entire process can be operated by one person, greatly saving energy waste and labor costs in wet granulation.

Principle: The materials in the silo are stirred by a mixer to remove air while stably feeding the horizontal feeder. After the material enters the horizontal feeder, it is driven by the rotating screw to gradually degas during the forward movement process, and the material with increased density is forcibly fed into the tablet press. The tablet press of the dry granulation machine rolls the high-density material conveyed by the horizontal feeder into 2-4mm thin sheets through a pair of hydraulic cylinders (adjustable pressure) and completes the degassing process again. The rolled thin sheet is cut into easily whole pieces by the cutting teeth of the shearing crusher and then falls into the granulator. The fragments are forcibly squeezed out of the sieve plate under the pressure of the whole blade. After screening, the extruded particles can obtain the product with the desired particle size for the customer. At this point, the dry granulation machine has completed the entire granulation process.

There are actually various types of dry granulators, such as fully automatic dry granulators, laboratory dry granulators, pharmaceutical dry granulators, and so on. The dry granulation technology can be achieved through a drum flat press granulator. Dry granulation machine: The extract of traditional Chinese medicine with a certain relative density is dried by spray to obtain dry extract powder. After adding certain auxiliary materials, it is pressed into thin pieces by dry extrusion granulator, and then crushed into particles.Dry granulation machineLess auxiliary materials are required, which is beneficial for improving the stability, disintegration, and dispersibility of the particles.

The dry granulation machine is particularly suitable for drug controlled granulation that cannot be achieved by traditional wet granulation and is unstable under humid and hot conditions. In addition, the dry granulation machine does not require any intermediate additives, and the particle size of the product after granulation is uniform. Reduce powder waste, minimize environmental pollution, and facilitate later processing, storage, and transportation. The new dry granulation process can replace the input of wet granulation assembly lines, reduce manpower, material resources, and financial resources, and is currently the most energy-efficient and environmentally friendly equipment in the industry.

The production of more environmentally friendly dry granulation machines reduces the manpower and material resources invested in pharmaceuticals, greatly reducing the cost of pharmaceuticals and providing impetus for the stability of related industries. Energy conservation and environmental protection are currently hot topics, and many industries consider green energy conservation as a future development trend. For dry granulation machines, energy conservation and environmental protection are also the trend.