As an important equipment in the food packaging industry, granulators have been constantly developing and innovating. The granulation mechanism has fast granulation and good effect. It is designed with a special hole filter screen, carefully screened, and its friction filter rod can crush the solid particles of the sieve. It is widely used in the pharmaceutical, chemical, and food industries.

　　

The dry granulation machine is a one-step granulation method following the second-generation granulation method'A granulation method developed later is an environmentally friendly granulation process, which directly compresses drug powder into granules using a new equipment. Dry granulation machines are widely used in industries such as pharmaceuticals, food, and chemicals for granulation, especially for materials that are prone to decomposition, failure, or agglomeration when exposed to moisture and heat. The granules made by the dry granulation machine can be directly compressed into tablets or filled into capsules.

　　

It is understood that the dry granulation machine uses roll pressure control technology, and the control equipment of this equipment can adjust any physical property fluctuations between different materials and different batches of the same material, so that the process parameters of dry granulation can be repeatedly adjusted, thereby producing high-quality granules. Dry granulation technology can be achieved through a drum flat press granulator. The extract of traditional Chinese medicine with certain relative density is dried by spray to obtain dry extract powder. After adding certain auxiliary materials, it is pressed into thin pieces by dry extrusion granulator, and then crushed into particles. This method requires fewer excipients, which is beneficial for improving the stability, disintegration, and dispersibility of particles.

　　

In the future, dry granulation machines will meet the requirements of cleanliness and flexible functionality. Firstly, a sealed dry granulation system can reduce dust pollution during the production process, thereby lowering the risk of pollution and contamination; Secondly, the equipment adopts a modular design, and the entire granulation device can be disassembled with only a small number of tools, making it easy to clean all module units. The screws and rollers can also be easily replaced to adapt to different granulation tasks.

　　

With the continuous development of the food packaging market, people's expectations and requirements for the food packaging industry are also increasing. The application of new granulation technology can greatly improve the preparation efficiency and product quality of traditional Chinese medicine granules. Therefore, in the development process after the granulator, attention should be paid to technological innovation, constantly pushing new ideas with market changes, and meeting the requirements of clean and flexible industries.

Analysis and prediction of future development trends of dry granulation machines

In the process of traditional Chinese and Western medicine pharmaceuticals, the granulator plays a crucial role. With the continuous development of the pharmaceutical market, people's expectations and requirements for the pharmaceutical industry are also increasing. In order for pellet machines to have better development in the future, they must constantly innovate with market changes.

The rotary granulator has fast granulation speed and good effect. It is designed with a special hole filter screen, carefully screened, and its friction filter rod can crush the solid particles of the screen filter. It is widely used in the pharmaceutical, chemical, and food industries. This machine can replace the swing pellet machine and is a new generation pellet equipment. It is a type of powder material that uses the swinging effect of a rotating drum to grind wet powder raw materials into particles through a stainless steel sieve. It can also be widely used to crush already formed blocks into ready-made particles. In the field of chemical drugs, it is used to grind wet powder into particles, which are dried and used to press tablets. It can also crush blocks that have solidified during storage or clumped during chemical processing.

The dry granulation machine is an updated granulation method developed after the second generation granulation method of "one-step granulation". It is an environmentally friendly granulation process and a new equipment that directly compresses drug powder into granules. Dry granulation machines are widely used in industries such as pharmaceuticals, food, and chemicals for granulation, especially for materials that are prone to decomposition, failure, or agglomeration when exposed to moisture and heat. The granules made by the dry granulation machine can be directly compressed into tablets or filled into capsules.

The dry granulation machine uses updated roll pressure control technology, and the control equipment of this equipment can adjust any physical property fluctuations between different materials and different batches of the same material, so that the process parameters of dry granulation can be repeatedly adjusted to produce high-quality granules. Dry granulation technology can be achieved through a drum flat press granulator. The extract of traditional Chinese medicine with a certain relative density is dried by spray to obtain dry extract powder. After adding a certain amount of auxiliary materials (or not depending on the composition of the materials), it is pressed into thin pieces by a dry extrusion granulator, and then crushed into particles. This method requires fewer excipients, which is beneficial for improving the stability, disintegration, and dispersibility of particles.

In the future, dry granulation machines will meet the requirements of cleanliness and flexible functionality. Firstly, a sealed dry granulation system can reduce dust pollution during the production process, thereby lowering the risk of pollution and contamination; Secondly, the equipment adopts a modular design, and the entire granulation device can be disassembled with only a small number of tools, making it easy to clean all module units. The screws and rollers can also be easily replaced to adapt to different granulation tasks.

The application of new granulation technology can greatly improve the preparation efficiency and product quality of traditional Chinese medicine granules. Therefore, in the development process after the granulation machine, attention should be paid to technological innovation to meet the requirements of clean and flexible industries.

That's why Zhangjiagang Aiguo Biotechnology Co., Ltd. has independently designed and developed based on the needs of domestic and international markets and the absorption of foreign Xianjin technologyLGCSeries vertical feeding dry granulation machine. Compared to traditional wet granulation, dry granulation has the ability to directly produce granular products from powder raw materials that meet user requirements, without the need for any intermediates or additives. After granulation, the product has uniform particle size and significantly increased packing density, which not only controls pollution but also reduces powder and energy waste, improving material appearance and flowability. Dry granulation machine is an updated granulation method developed after the second-generation granulation method of "one-step granulation". It is an environmentally friendly granulation process and a new equipment that directly compresses drug powder into granules. Dry granulation machines are widely used for granulation in industries such as pharmaceuticals, food, and chemicals. They are particularly suitable for granulation materials that are prone to decomposition, failure, or agglomeration when exposed to moisture and heat. The granules produced by dry granulation machines can be directly compressed into tablets or filled into capsules. The design of the dry granulation machine meets the regulatory and technical requirements of the pharmaceutical industry(1)The granulation device and the power device are spatially separated;

(2)The vertical arrangement of pressure rollers eliminates the influence of gravity;

(3)The equipment design complies withGMP；

(4)Two stage screening and granulation system to ensure the production of particles that meet the requirements;

(5)Made of medical grade stainless steel;

(6)All non-metallic materials comply withFDARelated requirements;

(7)automationPLC；ISO9001Multiple certifications including quality management system certification. The product has various types10 remainder.

The equipment of Zhangjiagang Aiguo Biotechnology Co., Ltd. is sold to South Korea, Iran, Türkiye, Algeria, Tunisia, Egypt, and many large domestic pharmaceutical enterprises. with2016 New version of the national pharmaceutical industry in the yearGMPWith the end of the standard, dry granulation will surely usher in broader development prospects and create more brilliant achievements.

Characteristics of laboratory dry granulation machines and intelligent dry granulation machines produced by Aiguo Biotechnology

granulatorAdvantages:

●The bearings and pressure rollers of the Tian Nong Technology Granulator use a closed-loop lubrication system,Real time tracking, monitoring, and display of the temperature of the pressure roller and pressure chamber using a microcomputer,*Solved the problem of relying on experience lubrication for roller lubrication, ensuring continuous production of granulation.

●The driving gear adopts high-precision gear transmission,Using professionally customized high-quality bearings,Ring mold quick release clamp type,Increased output compared to belt type10-15%左右。

●ring die,The pressure roller uses alloy steel(stainless steel)Forging precision machining,Adopting carburizing process for heat treatment,The height of the carburizing layer is up to2mm,canzuiGreatly saving production costs.

●Specially designed compression chamber extends the life of the mold, and under the same model and quality of the mold, the life can be extended by up to70%左右。

●The specially designed compression chamber has poor sensitivity to the moisture content of the material, and the moisture content of the material is higher than that of the same model10%Both can be granulated normally, thereby saving material drying costs.

●The pressure chamber monitoring system of Tiannong Technology solves the problem of high temperature hazards caused by illegal operations in the pressure chamber, effectively preventing Dust explosion and fire hazards caused by high temperature inside the suppression chamber.

●The tempering device and ring mold protective cover are all made of stainless steel to prevent corrosion and damage caused by long-term use of water vapor.

●The interlocking function between the position controller of the ring mold safety protection cover and the host electrical equipment ensures that during mechanical operation, if the ring mold safety cover is illegally opened, the main motor will automatically shut down to prevent harm to personnel caused by adjusting the operation of the machinery.

●A specially designed overload protection device for the granulator. When the granulator is overloaded or metal foreign objects enter, the safety pin of the protection device will automatically disconnect, and the safety pin position control switch will cut off the power supply of the main machine, protecting the ring mold, pressure roller, etc. from serious damage.

●Convenient and efficient particle length cutter, allowing you to freely choose the particle length you need.

●Fully enclosed forced feeding mechanism, with an integral motor structure for higher safety.

●There is a quick discharge port below the forced feeding screw, which can be quickly opened to prevent the occurrence of machine blockage during illegal operations.

●Tiannong's self-developed integrated pressure roller oil injection device belongs to domestic and foreign peers*The technology ensures that each pressure roller is lubricated and there will be no leakage of injection.

●Specially designed spindle and hollow shaft structure, there is no need to worry about spindle and hollow shaft deformation or fracture accidents.

●The ultra long service life of the roller bearing is extended to the limit of its lifespan8000More than hours.

●Adopting large modulus gears, the design parameters are several times the actual power, and the gear life can reach ten years.

●The specially designed box structure is more than twice the weight of the same model, giving the granulator strong mechanical power requirements.

●There is a quick entrance for mold polishing materials to prevent waste and contamination of other mechanical parts.