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E-mail
15093177890@163.com
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Phone
15093177890
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Address
B06-1 Qidi Zhenghang Intelligent Manufacturing Industrial Park, Intersection of Xinxiang Road and Luoning Road, Shangjie District, Zhengzhou City, Henan Province
Zhengzhou Kewangda Biological Instrument Co., Ltd
What are the process principles and characteristics of vacuum freeze-drying machine?
Date: 2025-11-06Read: 16
The process principle of vacuum freeze dryer (freeze dryer) is based on the three state change of water. Through a low-temperature vacuum environment, the ice in the material is directly sublimated into water vapor, thereby achieving efficient drying. The core process is divided into three stages:
1. Pre freezing stage: Quickly cool the material to -30 ℃ to -50 ℃ to completely freeze the moisture into ice crystals, avoiding structural damage.
2. Sublimation drying stage: Under vacuum (pressure below 610.5Pa) and low temperature (-20 ℃ to 0 ℃) conditions, ice directly sublimates into water vapor, and about 90% of the water is removed by a water trap.
3. Analysis of drying stage: Increase the temperature appropriately (20 ℃ to 40 ℃) to remove bound water, and the final residual moisture should be less than 5%.
The vacuum freeze dryer mainly has the following characteristics:
1. Retain active ingredients: Low temperature drying to avoid deactivation of thermosensitive substances such as proteins and vitamins.
2. Structural Porosity: After drying, the material is loose and porous, with good rehydration properties, approaching a fresh state.
3. Long term storage: Vacuum environment inhibits microbial growth and extends shelf life.
4. Widely applicable: suitable for fields such as medicine, biological products, high-end food, etc.
This technology achieves high-quality drying of materials through precise control of temperature and vacuum degree, becoming a key equipment in the high-end field.
