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Zhongsilifu (Tianjin) Biotechnology Co., Ltd

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    zhongsilifu@163.com

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    Intersection of Sanshui Road and Fenglin Road, Hexi District, Tianjin

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Brief Introduction


2024The freeze-drying technology training camp in September will be held in Tianjin. We sincerely invite experts, scholars, senior R&D personnel, quality personnel, and production personnel in the fields of pharmaceuticals, medical, biotechnology, and scientific research from all over the country to attend.

Time: The 23rd, 24th, and 25th are advanced training courses on freeze-drying technology, including practical courses on freeze-drying samples;

26Daily expert boutique class.

Topic: Development of Freeze Drying Technology in Various Application Fields Freeze Drying Technology Training

Main content: Release the latest application and development technologies of freeze-drying in pharmaceuticals, IVD reagents, biotechnology, and big health.

Characteristic: Conduct a special analysis of new freeze-drying technologies related to the development of freeze-drying technology in application fields.

Reason for entry: Rich experience in freeze-drying design in the industry, combined with theory and practice. Mr. Ye Minghui and Mr. Chen Youlin, domestic experts, brought about a brilliant and diverse technical sharing.

The scope of this freeze-drying technology training camp includes: detailed explanation of freeze-drying application technology, including freeze-drying mechanism, freeze-drying component design, freeze-drying process design, freeze-drying production line design, and application cases of freeze-drying technology in various fields. At the same time, there are rich practical design stages where you can have in-depth discussions with teachers from Boyikang Freeze Drying Laboratory on the details of freeze-drying design and production, as well as the use of freeze-drying machines and the problems encountered during the freeze-drying process. The advanced design technology of freeze-drying process is the core content of this training camp. Train and assess qualified personnel, and issue training certificates.

this timeFreeze drying technologyAll participants in the training camp are allowed to carry freeze-dried products for practical freeze-drying operations. Freeze dried products include bottled, palletized, or other types of loaded materials. The practical operation can simulate the actual freeze-drying production scaling process, and the practical freeze-drying machine specifications are 2 ㎡, 3 ㎡, and 5 ㎡ production type freeze-drying machines.

Lecturer Introduction:

Mr. Ye Minghui: Founder of Boyikang Freeze Drying Laboratory, international freeze-drying expert, with 25 years of experience in freeze-drying process research, and has participated in major national pharmaceutical research projects multiple times, responsible for freeze-drying technology and conducting in-depth research in the field of pharmaceutical freeze-drying. We have rich experience in coupling drugs, liposome drugs, fusion proteins, freeze-dried vaccines, and IVD diagnostic reagent freeze-drying, and have developed dozens of product formulas with significant economic benefits.

Mr. Chen Youlin: Currently serving as the director of the Boyikang Freeze Drying Technology Research Center, a domestic freeze-drying expert specializing in IVD reagent development and biopharmaceutical freeze-drying formulation development. He has expertise in freeze-drying microspheres POCT、 I have over ten years of development experience in multi joint molecular testing projects, especially proficient in the development of molecular diagnostic reagents and freeze-drying of coupled drugs.


The schedule of the technical advanced training course meeting is as follows:

Course schedule on the 23rd

08.30-09:00

Opening Ceremony

09:00-12:00


1. Design of stem cell and extracellular vesicle formulations, as well as freeze-drying formula design

2. Design of collagen, collagen like formulations, and freeze-drying vehicles

3. Optimization of freeze-drying process of gel materials such as hydrogel and aerogel

Speaker: Sun Wen, Chen Youlin

12:00-13:00

lunch

13:00-18:00



4. Research and Design of Medical Beauty Freeze Dried Powder Project

5. Design and optimization of freeze-drying protectants for antibody drugs, fusion protein drugs, and liposome drugs

6. Design scheme for freeze-drying activity of pharmaceutical strains/probiotics

7. The influence of packaging materials, liquid loading capacity and other factors on the design of freeze-drying curve

Speaker: Fang Yuli, Chen Youlin, Sun Wen

18:00

dinner party

Course schedule on the 24th

08:30-12:00

8. Design and optimization of freeze-drying formulation for diagnostic reagents

9. Large scale freeze-drying production

10. Microsphere freeze-drying and packaging assembly line system

Speaker: Chen Youlin and Fang Yuli

12:00-13:00

lunch

13:00-17:00






Application Design of Freeze Drying Machine Technology (Practical Step)

There are three major sectors in total

1. Microsphere preparation and freeze-drying design

Design a liquid system and add protective and shaping agents, and perform microsphere liquid nitrogen molding. After packaging, perform freeze-drying validation.

2.Freeze drying curve design

Test the configured solution and record the Te and Tm values. Design freeze-drying curves based on different packaging materials, liquid loading height, and loading capacity, and conduct freeze-drying validation.

Students can bring their own solutions and packaging materials, or use the solutions and packaging materials prepared for the training camp.

Students can bring their own raw materials or use the materials prepared by the training camp

Specific arrangement: Divide the students into groups and have Boyikang laboratory staff cooperate to design, practice, and verify the entire freeze-drying process

Guidance teacher: Chen Youlin, Sun Wen, Fang Yuli

17:00

dinner party

Course schedule on the 25th

8:30-9:30

Application Design of Freeze Drying Machine Technology (Practical Step)

Collect, process, evaluate and analyze the practical samples from the previous day

Guidance teacher: Chen Youlin, Sun Wen, Fang Yuli

9:30-12:00

Application Design of Freeze Drying Machine Technology (Practical Step)

There are three major sectors in total

3.Protein freeze-drying activity design

Based on the learned theory, design protective and shaping agent formulas, prepare liquids, conduct freeze-drying validation, and test activity.

Students can bring their own enzymes or use enzymes prepared for the training camp.

4.Freeze drying curve design

Test the configured solution and record the Te and Tm values. Design freeze-drying curves based on different packaging materials, liquid loading height, and loading capacity, and conduct freeze-drying validation.

Students can bring their own solutions and packaging materials, or use the solutions and packaging materials prepared for the training camp.

Students can bring their own raw materials or use the materials prepared by the training camp

Specific arrangement: Divide the students into groups and have Boyikang laboratory staff cooperate to design, practice, and verify the entire freeze-drying process

Guidance teacher: Chen Youlin, Sun Wen, Fang Yuli

12:00-13:00

lunch

13:00-15:00

11. Raw material freeze-drying fully automatic feeding and discharging system

12. Washing, drying, filling, rolling, freeze-drying linkage system

Speaker: Sun Wen, Fang Yuli, Senior Craft Expert

15:30-17:00

Review courses and take exams

Sort out and review the key points explained in the course

Q&A session, answering questions, reviewing knowledge points

Exam session, 60 minutes of exam time, and grading to determine the level

Guidance teacher: Chen Youlin, Sun Wen, Fang Yuli, Ye Minghui

17:00

dinner party


The schedule of the expert boutique class meeting is as follows:

Course schedule on the 26th

08:30-12:00

Research on the characteristics of freeze-drying protectants: In depth analysis of the characteristics and effects of commonly used freeze-drying protectants, including the state, dosage, characteristics, effects, and how to combine with other protectants of each protectant.


Speaker: Ye Minghui

12:00-13:00

lunch

13:00-17:00



Research on the combination of freeze-drying formula and freeze-drying curve: Differences in standard freeze-drying curve design, multi combination grid freeze-drying formula evaluation, multi combination grid freeze-drying curve evaluation, and freeze-drying curve design for screening freeze-drying formulas.


Speaker: Chen Youlin

17:00

dinner party


Conference Content Preview:

1 Mainly based on practical experience, supplemented by theory, and biased towards practical cases.

2 Analysis of common issues with biopharmaceutical freeze-drying products, including protective agent development, process design, and quality control.

3 Formula screening mechanism:How to carry out the scientific design of single factor method and multi factor method.

Advanced Technology Training CourseParticipation fees:6000yuan/person.

Expert Boutique ClassParticipation fees:6000yuan/person.

Note: The advanced technical training course is suitable for preliminary freeze-drying R&D personnel, while the expert boutique course is suitable for expert level personnel who have been engaged in freeze-drying technology for many years. Users can choose to participate in both classes or only one class according to their own needs.

    Date: September 23rd, 24th, 25th, 26th, 2024

Quota: 25 people in total, small class system. Those who register beyond the quota will be included in the next training camp

Location: No. 23 Guangyi Road, Xiazhuzhuang Industrial Park, Wuqing Development Zone

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