Large scale ultrafine crusher

NegotiableUpdate on 01/04

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Nature of the Manufacturer: Producers

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Overview

Large scale ultrafine pulverizer: After tens of thousands of wall (membrane) micro pulverization experiments, a large amount of successful practical experience has been accumulated. The ultrafine pulverizer produced by the company has the characteristics of high pulverization efficiency, high wall breaking rate, low pulverization temperature, and fully enclosed operation; It belongs to the common technology for the preparation of micro (nano) Rice noodles and micro (nano) meter practical technical products; The particle size of the powder can reach 1-0.1; #181; m， The cell wall (membrane) rupture rate is over 98%; The application scope involves industries such as pharmaceuticals (including veterinary drugs and pesticides), (health) food, cosmetics, chemical building materials, metallurgical energy, electronic environmental protection, etc;

Product Details

　　Large ultrafine crusher:

Yantai Huibao specializes in productionUltra fine pulverizer (cell wall breaking machine)And engaged inMicro (nano) Rice noodlesA technology-based enterprise that specializes in technology, processes, equipment, and technical services. The company has combined powder technology with traditional Chinese medicine to study the characteristics and particle size of over 2000 types of Chinese medicinal materials. Through tens of thousands of wall breaking (membrane breaking) micro crushing experiments, it has accumulated a wealth of successful practical experience. The ultrafine pulverizer produced by the company has the characteristics of high pulverization efficiency, high wall breaking rate, low pulverization temperature, and fully enclosed operation; It belongs to the common technology for the preparation of micro (nano) Rice noodles and micro (nano) meter practical technical products; The particle size of the powder can reach 1-0.1 μ m, and the cell wall (membrane) breaking rate is over 98%; The application scope involves industries such as pharmaceuticals (including veterinary drugs and pesticides), (health) food, cosmetics, chemical building materials, metallurgical energy, electronic environmental protection, etc; And received positive feedback and praise from users.

　　Micro powder machineApplication in Traditional Chinese Medicine Pharmaceutical Engineering

Based on the combination of theory and practice, with the aim of practicality, achieve a complete solution for users.

For several years, the company's experimental technology personnel have continuously conducted tens of thousands of crushing experiments for users in various traditional Chinese medicine industries across the country, including pharmaceuticals, scientific research, universities, enterprises, hospitals, etc. Nearly a thousand varieties of traditional Chinese medicine and hundreds of traditional Chinese medicine formulas have been developed, forming a complete set of cell level micro crushing process conditions for traditional Chinese medicine. Due toCell level micro pulverization of traditional Chinese medicineThe variety of crushing varieties is diverse, and the subsequent units of micro crushing are different from conventional ones. In the work, emphasis is placed on personalized analysis of raw material characteristics and user requirements. Corresponding systems have also been formed for related issues such as raw material processing, subsequent formulations, packaging and storage.

The company has made countless modifications to the appearance, crushing effect, material adaptability, operability, maintainability, cleaning performance, noise, long-term continuous operation reliability of equipment, human factors affecting operators, regional differences, site differences, etc. of the equipment. Lay a solid foundation for the stability of product quality.

The company provides users with a complete solution that includes standard cleaning SOP, standard maintenance SOP, and standard operation SOP. It has assisted several enterprises in completing GMP validation for traditional Chinese medicine micro crushing workshops.

　　Large ultrafine crusher:Technical characteristics

1. The crushing process is fully enclosed and non graded (preservation of drug components)

2. Effective compression and crushing method (increased bioavailability brought by precision compounding)

3. Unit operations before and after the process, quality control and GMP, other (standardization of equipment)

　　Micro powder machineworking principle

Under the action of external excitation force, the grinding medium undergoes a throwing motion that sometimes disperses and sometimes aggregates. The grinding medium itself rotates in the same direction, while the grinding medium group revolves. The inner and outer grinding media constantly exchange positions, and the two grinding media constantly collide, squeeze, and shear the material, causing it to be crushed and sheared. The particles are constantly broken from large to small. During the crushing process, larger particles are subjected to force first and are crushed first.

According to the working principle, particles composed of plant cell groups, whether composed of large cells or small cell groups, have equal opportunities for compression and impact as long as their overall size is comparable. In the process of crushing medicinal herbs, whether it is a large cell group or a small cell group, as long as their overall size is equivalent, the probability of being crushed is the same.

Solved various problems in crushing operations

Strong fibrosis (Ganoderma lucidum, Astragalus membranaceus, etc.), high sugar and high viscosity (Goji berries, Rehmannia glutinosa, etc.)

Resin based materials (frankincense, myrrh, etc.) with strong toughness (antelope horn, hawksbill turtle, etc.)

Animals (scorpions, centipedes, etc.) and oils (almonds, schisandra, etc.)

Excellent features and special performance

A、 High crushing efficiency: Suitable for any fibrous, high toughness, high hardness, and moisture content less than 6% material, with low energy consumption and low temperature, avoiding high-temperature oxidation, deterioration, and loss and segregation of active ingredients. The crushing process is completely sealed without dust spillage, fully improving the working environment.

B、 Strong crushing ability: no residue left after crushing. Suitable for both dry and wet crushing, water, alcohol, or other solvents can be added during wet crushing.

Suitable for crushing requirements with a central particle size of 150 mesh to 10000 mesh (1.3 μ m), and can reach 1 to 0.1 μ m when using special processes. Materials that require breaking cell walls, such as pollen and Ganoderma spore powder, have a breaking rate of over 95%.

C. GMP design: Designed according to GMP standards, made of stainless steel that meets national drug and food standards. The parts in contact with the materials are polished stainless steel, with internal corners and arcs that transition. The fully enclosed operation has no dust pollution or material loss.

D、 Easy to operate: compact and reasonable structure with small footprint, no need for air compressors, conveying pipelines, dust removal and collection devices, and can be put into operation by connecting water and electricity. Easy to assemble, disassemble, and replace materials; Can be cleaned and disinfected with water, starch, alcohol, etc; Equipped with a composite soundproof cover, the production noise is low.

E、 Easy to operate: low labor intensity, easy to operate, convenient for disassembly, cleaning, and daily maintenance.

F、 Complete models: There are both large and medium-sized equipment suitable for industrial production, as well as small equipment suitable for small-scale production or scientific research experiments.

G、 Application scope: Suitable for animals (plants), mineral medicinal materials, and (health) food raw materials with different species characteristics and significant differences, such as materials with toughness, brittleness, high (low) hardness, high fiber content, high oil or sugar content.

H、 Appearance: Fully enclosed stainless steel, made of matte stainless steel plate.

I、 Precision coating: It can perform precise particle composite and coating of two or more materials, high solid content strong homogenization, and strong emulsification operations.

J、 Low temperature quality crushing, crushing fresh Chinese herbs and animal fresh tissues.

K、 Temperature controllable: The crushing temperature can be controlled by adjusting the temperature and flow rate of the cooling water. When low-temperature crushing is required, the refrigeration system can be configured to achieve a minimum temperature of -45 ℃

Other process application methods

1、 Application in the cosmetics industry: After micro crushing the cell wall, the super effect time is shorter, the absorption is more complete, the efficacy is more comprehensive, and the effect is more obvious. Some fresh medicines can also be crushed and directly made into cosmetics.

2、 Application in the animal medicine industry: Micro powder technology is an effective means of implementing green animal medicine. (Traditional Chinese medicine) animal medicine can effectively improve efficacy, reduce costs, solve drug residues, and improve safety after cell wall breaking. Chinese medicine micro powder quickly disperses and suspends in water, and is supplied to livestock for normal drinking through an automatic water dispenser, effectively solving the problems of drug precipitation and uneven dosage that lead to reduced efficacy.

3、 Application of precious fine materials

4、 Precision mixing (achieving composite and precision coating with uniformity better than ± 1 ‰)

5、 The impact on molding (including coating)

a) For tablets and capsules, improve dissolution rate and enhance bioavailability; Improve appearance and uniformity of particle content; Reduced fiber elasticity makes it easier to pelletize and compress; Increase the specific gravity of the capsule to increase its filling capacity;

b) For soft capsules, improve the mixing uniformity between the main drug and the matrix, and reduce sedimentation; Due to the increase in the particle size of the main drug, the amount of matrix used can be correspondingly reduced, thereby lowering costs; Equal volume particles, thixotropy, particle size distribution, compression crushing

c) For ointment, gel and other external preparations, improve the mixing uniformity of the main drug and the matrix; Improve the delicacy of appearance; Reduced particle size facilitates transdermal absorption and improves therapeutic efficacy;