Triphenyl specific liquid chromatography instrument

Triphenylene (C18H14, also known as diphenylbenzene or biphenyl) is a class of closely related aromatic hydrocarbons, composed of a central componentbenzene ringComposed of two phenyl substituents, there are three isomers:o-Terphenyl、m-Terphenylandp-TerphenylThe commodity cascade triphenyl is generally a mixture of three isomers used in the production ofpctPolychlorinated terphenyl was previously used as a heat storage and transfer agent. Among the three isomers, triphenylene is the most common one, used in dye lasers andsunscreenRaw materials.

brief introduction

Triphenyl is a multidisciplinary research team composed of Spanish universities and research centers that has successfully developed a synthetic small molecule that can be integrated into the genetic material of AIDS virus to prevent its replication. The newly synthesized molecule can inhibit the production of viral genetic material from the infected nucleus to the cytoplasm, thus preventing viral replication and preventing other cells from being infected.

principle

AIDS virus or human immunodeficiency virus type 1 (HIV-1)

The genetic material is composed of ribonucleic acid, which encodes several proteins that can penetrate human cells and replicate within them.

role

Using this method, triphenylene inserts into the receptor of Rev in viral ribonucleic acid, preventing the interaction between the protein and the ribonucleic acid receptor. This interaction is essential for the genetic material of the virus to leave the infected cell nucleus and for the survival of HIV-1. The fact that triphenylene inhibits the production of viral genetic material in cells prevents other cells from being infected.

Triphenylene specific liquid chromatograph Triphenylene specific liquid chromatograph