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Laboratory Air Safety: A Hidden Line of Defense for Researchers
Date: 2025-10-28Read: 6

A tragedy occurred in a laboratory of a university in Shanghai. A doctoral student experienced gas leakage while operating a hydrogen sulfide steel cylinder due to ineffective opening of the fume hood. The leaked hydrogen sulfide accumulates indoors, and the student may first notice an odor, but as the concentration rapidly increases, their sense of smell is paralyzed and they quickly become unconscious. Due to no one present, the opportunity for rescue was missed, and unfortunately, he passed away.


HEALTH SCIENCE


Currently, the air quality in many laboratories is not optimistic. We often see scenes like this: the fume hood is in disrepair for a long time, and its effectiveness is greatly reduced; The experimenters were unable to wear protective equipment correctly when operating volatile drugs due to feeling inconvenient; The laboratory space is narrow and poorly ventilated, leading to the accumulation of harmful gases... These daily details expose many shortcomings in reality. Long term exposure to low concentrations of harmful air may cause dizziness, allergies, chronic respiratory diseases, and even irreversible damage to organs such as the liver and kidneys in laboratory personnel. This is not only a tragedy for personal health, but also a huge loss of scientific research and institutional assets.

01
National Occupational Health Standards


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GBZ 2.1-2019 Occupational Exposure Limits for Hazardous Factors in the Workplace Part 1: Chemical Hazardous FactorsThe core of this standard is the 'occupational exposure limit'. It sets legal concentration limits for hundreds of specific chemical substances in the laboratory, such as benzene, formaldehyde, various organic solvents, etc. Simply put, it requires the concentration of harmful substances in the laboratory air to be controlled at a level that will not cause health damage to almost all workers under long-term repeated exposure. It is a 'hard ruler' for assessing occupational health risks in laboratories and determining the effectiveness of ventilation facilities, and is the bottom line requirement for ensuring employee health.



02
Indoor Air Quality Standards



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GBT-18883-2022 "Indoor Air Quality Standards"This standard focuses more on creating an overall healthy and comfortable indoor environment. It not only focuses on a single chemical pollutant, but also comprehensively sets limits for various parameters such as physical, biological, and radioactive properties. For example, it has clear concentration limits for well-known pollutants such as formaldehyde, benzene, PM2.5, and also puts forward requirements for fresh air volume, temperature, humidity, etc. For laboratories, this means that we cannot just focus on a few experimental chemicals, but also pay attention to the comprehensive air quality of the entire space to ensure that the environment is fundamentally fresh and safe.



03
The Importance of Laboratory Air Safety

The core importance of laboratory air safety is not an independent concept, but deeply integrated into the daily operation, personnel support, and research quality of the laboratory. Its importance is reflected in the following very practical aspects:

1. The core guarantee of personnel health and safety, whether in drug research and development, biological experiments or clinical tests, operators may be exposed to chemical volatile gases, aerosols, pathogenic microorganisms (such as COVID-19, tubercle bacillus, etc. under normal control), allergens, etc. A malfunctioning ventilation system or incorrect operation may cause these harmful substances to accumulate in the laboratory, be inhaled by personnel, and directly lead to acute poisoning, chronic diseases, or infections.

2. The prerequisite for the accuracy of experimental samples and results is that in cell culture, microbiological experiments, and high-precision chemical analysis, particles, bacteria, and cross pollutants in the air are the "killers" of experimental results. For example, an open petri dish may render the entire experiment unusable due to a bacterial contamination in the air; A precise detection may deviate due to chemical interferences in the air.


04
The Development Trend of Laboratory Air Safety

The core concept of future laboratory air safety is to shift from "pipeline exhaust" to "self purification without pipelines". By using equipment such as ductless fume hoods with high-efficiency molecular filters (such as activated carbon) or high-efficiency particle filters (such as HEPA), pollutants such as chemical vapors or biological aerosols are directly adsorbed and purified at the source, and then the clean air is circulated back indoors. It also achieved significant cost reduction and efficiency improvement: it eliminates the expensive installation and maintenance costs of complex pipeline engineering, and because it no longer exhausts a large amount of air conditioning to the outside, it can greatly reduce energy consumption, allowing laboratories to layout and operate more flexibly and efficiently even with limited budgets.


05
Anruis Laboratory Air Safety Integrated Solution

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The overall air safety solution for Anruis Laboratory includesClean air type fume hoodInstrument protection cabinet, ceiling mounted air purifier, clean air chemical storage cabinet, intelligent chemical management cabinet.


06
Case Study


1、 Balance weighing cover: used for weighing highly active drugs,Complies with OEB 5 protection level standards and meets high-precision weighing requirements. If considering higher levels of protection, the option is to use a bag in bag out mode.

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(Balance weighing cover)



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(Bag in bag out balance weighing cover)




2、 Clean gas chemical storage cabinet:

Support single/dual card swiping permission management. The shelves inside the cabinet are made of polypropylene material and can be paired with pull-out storage units for easy access. In addition, various models such as light shielded, fire-resistant, and explosion-proof are also available to meet different storage needs.


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3: Clean air type fume hood: used for pre-treatment chemical experiments and instrument reflection experiments.

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4、 Instrument protective cabinet:

The top of the equipment is equipped with fans and filters to process volatile substances generated during large-scale instrument reactions, in order to protect personnel safety and the surrounding environment. In addition, there is a walk-in fume hood.

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5、 Chemical intelligent management cabinet: equipped with automatic weighing, QR printing, and QR scanning modules, information management of inbound and outbound inventory, online data query, and expandable sub cabinet management functions. In addition, there are also fire-resistant/RFID versions available

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6、 Ceiling mounted air purifier: targeting harmful gases, PM2.5, bacteria, and virus particles, effectively reducing pollutant concentrations and improving indoor environmental safety.

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