choiceBeonChipmicrofluidicsSix Reasons for Chips

BeonChipIt is a Spanish company specializing in the field of microfluidic technology, mainly producing or customizing microfluidic chips.2021yearIn July, Diancheng Biology and BEOnChipFormally reaching a strategic cooperation agreement, becomingBeonChipAgents of chips. At present,BEOn Chip develops 4 standard microfluidic chips: BE-GRANDIENT、BE-FLOW, BE-DOUBLEFLOW, and BETRANSFLOWThis article summarizesBEOnChipSix prominent advantages of microfluidic chips for users to better understandBeonChipChip.

1. Good biocompatibility

BEOnChipThe chip is composed ofCOP(Cyclic olefin polymer)Made of material, this material has good biocompatibility, can be compatible with living cells, tissues, and organs, will not cause damage to cells, is non-toxic, and has no risk of being rejected by the immune system.

2. Excellent optical properties

COP has excellent optical properties, with high transparency, low birefringence, and high Abbe number in the visible and near ultraviolet ranges. This material is an ideal choice for use in microscopes.

3. Good chemical and heat resistance

BeonChipChips have excellent chemical resistance, can resist acids and even polar solvents, can be produced using wet etching techniques, and are easy to clean and disinfect with alcohol. In addition, the glass transition temperature of the chip can reach up to180℃ is helpful for sensor integration and surface functionalization.

4. Selective adsorption is essential

Widely used in current laboratories and commercial platformsThe disadvantages of non selective adsorption of hydrophobic drugs in PDMS materials are different, COPIt has the characteristic of non selective adsorption, which helps to accurately deliver drugs and ensure the accuracy of experimental results.

5. easy to use

1) No bubbles&Easy to operate

BeonChipThe chip adopts a port design, which can tighten the connector without generating bubbles in the pipeline. The unique side wall design of the chip makes it easy for users to operate without touching the compartment.

2) Compatible with microscopes

BEOnChipThe chip size is consistent with the standard glass slide, and the observation position is96The position matching of the orifice plate, in addition, the chip is compatible with any type of optical microscope, such as bright field, fluorescence, confocal microscope, etc., making it easy for users to observe.

3) Compatible with microfluidic systems

BEOnChipThe chip is compatible with any microfluidic system, and users can connect the chip to their own microfluidic system using a simple connection kit.

6. versatile

1) Cell seeding, wrapping, and recycling

Users can utilizeBEOnChipChip processing2D. 3D cell culture or 2D、3D cell co culture can be used to establish a series of physiological organ models in vitro and conduct subsequent research using this chip. The processed cells can also be recovered for downstream analysis.

2) Interconnection and intercommunication

BeonCHip chips can be connected to each other. Therefore, by utilizing the combination of chips, users can easily create complex culture models or conduct cross-talk studies between different tissues.

3) Customization

In addition to standardized chips,BEOnChipChips also provide customized services, and customers can customize the volume of cell culture channels, chip substrates, chip membrane aperture, etc. according to their needs.