Flow chemistry (sometimes referring to intermittent flow, microchemistry, or continuous flow chemistry) innovatively integrates traditional independent and separate operational processes, accelerating the speed of research and development. Flow chemistry has emerged as a new production technology in the field of drug research and development. The Asia flow chemistry reaction system newly developed by Syrris in the UK can quickly optimize reaction processes and synthesize large amounts of organic compounds, especially under high-risk and difficult to implement reaction conditions, greatly promoting the development of green chemistry and laboratory automation. The Asia Flow Chemistry Reaction System is suitable for screening, optimizing, scaling up, and establishing chemical libraries in pharmaceutical chemistry, as well as organic chemistry research such as the synthesis of metal nanoparticles.
Application of Asian mobile chemistry synthesis:
Suzuki reaction: faster reaction and improved selectivity, with negligible Pd content in the product;
Hantash pyrrole synthesis: improving reaction rate and yield, one-step process;
Synthesis of metal nanoparticles: narrow particle size distribution, safe handling of corrosive reagents;
N-alkylation to produce primary amines: faster reaction and significant monoalkylation selectivity.