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The principle and application of ultra-high pressure nano homogenizer
Date: 2024-12-23Read: 9
Ultra high pressure nano homogenizer is a multifunctional experimental equipment widely used in materials science, chemical engineering, biomedical and other fields.
The working principle of the ultra-high pressure nano homogenizer is the high shear and impact forces generated in the sample gap between the homogenizer head and the clamping device. The sample is compressed and broken in the gap, generating a high-energy liquid mixture, which is homogenized and dispersed under high shear force of the sample.
Due to the use of liquid for physical force fragmentation, this method can produce very small particle sizes (usually reaching tens of nanometers), with narrow particle size distribution and high peak state. Homogenization is achieved by high-energy flying objects (water) hitting the surface of a substance, causing molecules on the surface to be excited by the impact, resulting in the production of some free radicals and excited states, which facilitate subsequent reactions.
Ultra high pressure nano homogenizers are widely used in the following fields:
1. Materials Science
The application of ultra-high pressure nano homogenizers in the field of materials science is very extensive. Researchers can crush, disperse, mix and other treatments of different materials through homogenization processes. Materials that have undergone homogenization treatment are easier to further process and apply.
2. Chemical Engineering
The homogenizer can achieve efficient mixing in liquid-liquid, liquid-solid, gas-liquid and gas-solid interface applications, and can also be used to prepare nanoparticles, micro lotion, colloidal liquids, etc., greatly reducing the time and energy consumption of chemical reactions.
3. Biomedical Science
The application of ultra-high pressure nano homogenizer has not only been widely used in the fields of materials science and chemical engineering, but also in biological research such as cell lysis, protein decomposition, and gene sequencing. Especially in drug preparation and formulation development, homogenizers can greatly improve the biological activity and stability of drugs.