The pharmaceutical tablet press mold can continuously produce tablets, improving production efficiency. Due to the use of mechanized production methods, the quality of tablets is more stable and reliable. The machine surface is made of stainless steel, and the turntable surface is polished to avoid cross contamination. It meets GMP standards and is equipped with a transparent visual window, which can observe the tablet pressing process at any time. The window can be opened for easy cleaning and maintenance. It can be used for various shaped tablets, double palladium tablets (double-sided printing), and is particularly suitable for tablet pressing of large tablets.
Measurement steps for pharmaceutical tablet press molds:
1. Appearance inspection:
-Carefully inspect the surface of the mold for defects such as cracks, missing edges, and deformation.
-Check the roughness of the mold, inspect the shape for curled edges, missing corners, bursting, and wear, etc. For engraving dies, ensure that the surface of the shape is bright to prevent sticking, unclear tablet writing, and stacking during tablet pressing.
2. Dimensional measurement:
-Measure the key dimensions of the punch, such as the depth of the tablet shape, total length, and working length, which are directly related to the thickness, weight, and hardness of the tablet.
-Check whether the inner diameter, outer diameter and other dimensions of the middle mold meet the requirements, and ensure the accuracy of the fit between the middle mold and the punch rod, mold ring and other components.
-Measure the concentricity, parallelism, and other positional tolerances of each component of the mold to ensure its stability and accuracy during the pressing process.
3. Assembly inspection:
-Install the molds in the correct order on the tablet press, check whether the connections between the components are firm and whether the tightness is appropriate.
-Manually rotate the test wheel of the tablet press, observe the operation of the mold, check for any jamming, interference, or other phenomena, and ensure that the mold can move smoothly during the tablet pressing process.
4. No load trial operation:
-Start the tablet press for no-load trial operation, check if the mold runs smoothly and without any abnormal sounds.
-Observe whether the pressure indication of the tablet press is normal, and check whether the position of each moving part is correct, such as whether the up and down movement of the punch rod is in place.
5. Small batch trial production:
-After the no-load trial run is normal, a small batch trial production is carried out. The finely ground and dried sample powder is evenly sprinkled on the lower pressing head of the mold, and the upper pressing head is manually pressed and rotated to make the sample powder uniform and smooth.
-Press the tablets according to the prescribed process parameters such as pressure and speed, and observe whether the quality of the tablets meets the requirements, such as hardness, thickness, weight differences, etc.
-Conduct random inspections on the trial production tablets to check whether their appearance, disintegration time limit, content uniformity and other quality indicators meet the requirements.