The laboratory spray granulator is widely used in scientific research and industrial research and development fields by virtue of its technical advantages such as accurate and controllable particle size (5~250 microns), low temperature and rapid drying, and wide spectrum of applicable materials (solutions, suspensions, emulsions, etc.). The following are its core application industries and typical scenarios:
1、 Pharmaceutical and Biotechnology
1. Drug formulation development
Solid dispersion: improve the bioavailability of insoluble drugs (such as anti-cancer drugs), and co dry the drug and carrier (polymer/sugar) to form uniform particles through spray drying.
Inhalation preparation: Prepare a dry powder inhaler (DPI) with a particle size controlled within the range of 1-5 μ m to ensure efficient drug deposition in the lungs.
Pellet coating: fluidized-bed spray technology realizes uniform coating of drug release layer or taste masking layer.
2. Biological active substance treatment
Drying of thermosensitive biological products such as enzyme preparations, vaccines, antibodies, etc., using low-temperature processes (40-50 ℃) to maintain protein activity.
Microencapsulation of probiotics, combined with protective agent (trehalose) to extend the shelf life of live bacteria.
2、 Chemical Industry and New Materials
1. Material synthesis
Battery materials: Spherical granulation of lithium battery positive electrode (lithium cobalt oxide, lithium iron phosphate) and negative electrode (silicon carbon composite material) precursors to enhance tap density and electrochemical performance.
Nanomaterials: dispersion and drying of titanium dioxide (TiO ₂), graphene and other nanoparticles to inhibit agglomeration.
2. Catalysts and functional chemicals
Particle size control of metal catalysts (palladium, nickel based) to improve specific surface area and catalytic efficiency.
Granulation and drying of chemical products such as dye intermediates, white carbon black, and resins.
3、 Food and Additives
1. Functional ingredient processing
Microencapsulation of vitamin C/E and amino acids to prevent oxidative deterioration.
Drying of natural essence (lemon oil, peppermint oil) to retain volatile flavor substances.
2. Dairy products and extracts
Spray granulation of milk powder, coffee extract and plant protein to maintain solubility and nutrition.
4、 Ceramics and Special Materials
1. Ceramic powder granulation
Spherical granulation of materials such as alumina, magnesia, and porcelain clay to enhance sintering density and finished product strength.
2. Electronic ceramics:
Particle size homogenization treatment of dielectric materials and piezoelectric ceramic precursors.
5、 New Energy and Environmental Protection
1. Energy materials:
Particle dispersion and drying of fuel cell catalyst (platinum alloy).
Controllable synthesis of solid electrolyte (LLZO) powder.
2. Environmentally friendly materials:
Optimization of granulation of molecular sieves and adsorbents.
