Wet granulation machine is a granulation equipment widely used in the pharmaceutical, food, feed, chemical and other industries. It mixes materials with binders to produce wet granules, thereby achieving granulation treatment of materials. The following is a detailed introduction to the working principle and application of wet granulation machine:
1、 Working principle
The working principle of a wet granulation machine mainly includes two steps: mixing and granulation:
1. Mixing: The material and binder (such as syrup, fluid infusion, etc.) are mixed in a cylindrical container by the action of a mixing paddle to form a moist soft material. During this process, the materials are thoroughly mixed and gradually form liquid bridges, gradually transforming into loose soft materials.
2. Granulation: After the mixed soft material reaches the appropriate state, it is cut into uniform wet particles by a high-speed cutting knife placed on the side. These wet particles maintain good fluidity and compressibility during the cutting process, providing convenience for subsequent processes.
2、 Application Fields
Wet granulation machines are widely used in various fields, and some of the applications are introduced as follows:
1. Pharmaceutical industry: used for preparing granular preparations such as tablets, capsules, etc. By thoroughly mixing drugs and excipients to form uniform particles, the bioavailability and stability of drugs can be improved.
2. Food industry: used for making various soft candies, jellies, pastries and other products. By adjusting the formula and process parameters, it is possible to manufacture foods with different tastes and flavors.
3. Feed industry: used for making feed additives, fish feed, livestock feed, etc. Wet granulation machine can mix different types of feed materials and make them into granules, which is convenient for animals to feed and digest.
4. Chemical industry: used for processing various inorganic salts, catalysts, and other chemical substances. By using a wet granulation machine, these substances are converted into particles with a certain shape and size for subsequent processing and use.