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E-mail
tiantai@ttzyjx.com
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13327798188,13951156633
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No. 557-559, Gangkou East Road, Gangkou Town, Taizhou City
Taizhou Tiantai Pharmaceutical Machinery Factory
Taizhou Tiantai Pharmaceutical Rapid Granulator: An Efficient and Compliant Equipment for Particle Processing in Pharmaceutical Production
Date: 2025-09-01Read: 8
In the production process of oral solid preparations (such as tablets and capsules) in the pharmaceutical industry, the uniformity and flowability of particles directly affect the stability and drug quality of subsequent compression and filling. Traditional granulation equipment often has problems such as low processing efficiency, large particle size deviation, and high difficulty in cleaning, making it difficult to adapt to the high efficiency and compliance requirements of pharmaceutical production. Taizhou Tiantai Pharmaceutical is deeply engaged in the research and development of pharmaceutical equipment and has launchedFast granulatorWith the core advantages of "efficient processing, precise particle control, and compliant cleanliness", it has become a key equipment in the particle post-treatment process of pharmaceutical enterprises, effectively solving the pain points of traditional equipment.
1、 Targeted structural design: meeting the core requirements of pharmaceutical production
The structural design of Tiantai Pharmaceutical's rapid granulator revolves around the two core values of "efficiency" and "cleanliness" in pharmaceutical production, optimizing the entire process from feeding to discharging
Dual speed mixing and graded granular structureThe equipment adopts an integrated design of "mixing and crushing+grading and screening", with independent speed regulation of the mixing blade and the whole granule knife - the mixing blade disperses the block shaped material at low speed (50-150rpm) to avoid excessive crushing and excessive fine powder; The whole grain cutter is used to accurately round the dispersed material at high speed (300-800rpm), and is equipped with a replaceable stainless steel mesh (10-80 mesh optional) to quickly control the particle size within the range of 0.2-2mm, meeting the requirements of different formulations for particle size. The qualified rate of particles after finishing is stable at over 98%.
Fully enclosed and easy to clean designThe contact parts between the equipment and materials are made of 316L stainless steel, and the surface is polished with a mirror finish (roughness Ra ≤ 0.4 μ m), with almost no dead corners or depressions, effectively avoiding material residue; At the same time, the equipment adopts a fully enclosed chamber design, and both the inlet and outlet are equipped with silicone sealing gaskets to prevent dust leakage, ensuring a clean production environment and meeting the dust control requirements of pharmaceutical production. In addition, the chamber can be quickly disassembled, and the replacement and cleaning of the screen and stirring blade can be completed without tools. The cleaning time is reduced by 50% compared to traditional equipment, greatly improving the efficiency of production batch replacement.
2、 Core technological advantages: efficiency, stability, and compliance in one
Tiantai Pharmaceutical's rapid granulator achieves a balance between "efficient processing" and "quality assurance" in terms of technical performance through multiple innovations:
Ultra high processing efficiencyIn response to the demand for batch particle processing in pharmaceutical production, the effective capacity of the equipment can reach 30-100L (customizable according to production capacity), and the single batch processing capacity can reach 50-200kg (taking traditional Chinese medicine particles as an example). The whole particle speed is 60% faster than traditional equipment, and it can run continuously for more than 8 hours, adapting to the batch production rhythm of medium and large pharmaceutical production lines.
Precise temperature control and material protectionConsidering that some drug particles (such as thermosensitive traditional Chinese medicine ingredients and antibiotic particles) are sensitive to temperature, a jacket type cooling system is equipped on the outside of the equipment chamber, which can control the temperature inside the chamber at 25-35 ℃ by introducing circulating cooling water to avoid material deterioration caused by friction heating during the granulation process and ensure the stability of the effective ingredients of the drug.
Compliance and intelligent controlThe equipment complies with pharmaceutical industry compliance standards such as GMP and FDA, and key components are provided with material certification and verification documents to support users in equipment verification (IQ/OQ/PQ); At the same time, it is equipped with a PLC touch screen control system, which can preset the whole grain parameters of different materials (such as speed and mesh size), support parameter storage and calling, reduce manual operation errors, and have the function of recording operation data, making it easy to trace the production process.
3、 Exclusive applications in the pharmaceutical field: covering the production of multiple categories of formulations
Thanks to its professional performance, Tiantai Pharmaceutical's fast granulator has been widely used in the particle processing of various oral solid preparations in the pharmaceutical industry
Chemical drug preparationsUsed for the whole granule of raw materials in the production of tablets and capsules, ensuring consistent particle flowability and avoiding problems such as excessive weight difference and fragmentation during tablet pressing;
Traditional Chinese Medicine preparationSuitable for the whole granules of traditional Chinese medicine extract and powder, the anti sticking wall design of the equipment can effectively reduce material loss and ensure particle uniformity due to the characteristics of easy moisture absorption and high viscosity of traditional Chinese medicine granules;
Health product preparationsUsed for the whole granules of vitamins, probiotics and other health products, the low-temperature treatment process can protect the active ingredients and meet the strict quality requirements of health product production.