In modern scientific research, precise and efficient analytical tools are key to driving innovation and discovery. Thermo Scientific, a heavyweight product launched by Thermo Fisher Scientific ™ Orbitrap ™ Ascend Expert Tribrid ™ Mass spectrometer, with its outstanding versatility and ease of use, is more focused on enhancing your scientific research capabilities: its built-in intelligence and revolutionary Thermo Scientific ™ Tribrid ™ The excellent performance brought by the structure is demonstrated in proteomics quantification, characterization of complex peptide mixtures, and analysis of small molecules and higher-order structures.
Product Highlights
1The versatile Orbitrap Ascend Expert Tribrid mass spectrometer integrates multiple innovative technologies to meet the needs of multi omics research, including proteomics, metabolomics, lipidomics, glycoproteomics, and more.
2Excellent sensitivity and resolution, this mass spectrometer is equipped with an Orbitrap mass analyzer with a resolution of up to 480000 FWHM and a collection rate of up to 45 Hz. It can achieve high sensitivity and resolution analysis for both low abundance and complex samples.
3The Orbitrap Ascend Expert Tribrid mass spectrometer supports six fragmentation modes, including CID, HCD, ETD, EThcD, ETciD, and UVPD. These diverse fragmentation methods can comprehensively characterize the molecular structure in the sample and provide richer analytical data.
4Innovative designs such as Auto Ready ion sources and electric ion funnels enable mass spectrometers to perform automated remote calibration and efficient ion transfer, greatly improving laboratory productivity and data consistency.
5Focus on efficient and precise analysis. The new platform includes a softer ion source, a new front ion routing multipole rod, and an Auto Ready ion source for calibration. These characteristics make the instrument perform well in whole proteome quantification, characterization of complex peptide mixtures, and analysis of small molecule and higher-order protein structures.
6Improved experimental flexibility and performance: This mass spectrometer improves the capture of unstable compounds while maintaining optimal ion transport. Due to higher sensitivity and scanning rate of MS/MS, short gradient analysis performs well. Tandem Mass Tag ™ (TMT ™) The depth, accuracy, and precision of the analysis are unparalleled.
Application field
1 Proteomics:
In proteomics research, the Orbitrap Ascend Expert Tribrid mass spectrometer can achieve high-throughput multiplex quantitative analysis. By utilizing TMT multiplex isotope labeled quantitative reagents and SPS MS3 method, researchers can achieve high protein coverage while improving quantitative accuracy.
2 Metabolomics:
This mass spectrometer supports the SQUAD workflow and can perform both non targeted screening and targeted quantitative analysis simultaneously. Even with small sample sizes, efficient metabolite labeling and quantitative analysis can be achieved, significantly improving the efficiency of metabolomics research.
3 Lipidomics:
The Orbitrap Ascend Expert Tribrid mass spectrometer performs well in lipidomics research. Through fragmentation methods such as HCD and CID, the structure of lipid molecules can be comprehensively characterized. Using AcquireX software, researchers can identify more types of lipids in the same amount of time.
4 Glycoproteomics:
In glycoproteomics research, this mass spectrometer can comprehensively characterize glycopeptide structures through ETD and HCD fragmentation, improving the accuracy of identifying and characterizing unstable post-translational modifications (PTMs).
The Orbitrap Ascend Expert Tribrid mass spectrometer is an ideal choice for multi omics research due to its outstanding performance and versatility. Whether it is proteomics, metabolomics, lipidomics, or glycoproteomics research, this mass spectrometer can provide efficient and accurate analysis results, helping scientists make breakthrough progress in their respective research fields.