In the development, quality control, and bioequivalence evaluation of transdermal drug delivery formulations, the accuracy and stability of transdermal diffusion testers directly determine the reliability of data. Tianjin Jingtuo Instrument is deeply involved in the field of precision analytical instruments and has developedTransdermal diffusion testerWith advantages such as compliance with international standards, intelligent control, and high stability, it has become the preferred choice for pharmaceutical companies, research institutes, and testing institutions, providing strong support for the development of transdermal drug delivery technology.
1、 Benchmarking against national standards to establish a solid foundation for compliance in testing
This instrument is manufactured strictly in accordance with domestic and international standards such as the Pharmacopoeia of the People's Republic of China (2020 edition), USP, EP, etc., to ensure compliance in testing. Adopting a vertical diffusion cell structure with a precise volume control of 5-20mL (customizable), the cell body is made of high borosilicate glass, which has excellent chemical stability and transparency, avoiding interference with the sample. At the same time, the diffusion pool has excellent sealing performance, with a leakage rate of less than 0.1%, effectively preventing contamination or concentration changes in the received liquid, laying the foundation for obtaining key parameters such as drug transdermal rate and permeability coefficient.
2、 Accurate temperature control and mixing to enhance data reliability
Temperature and stirring rate are the core factors affecting drug transdermal diffusion. The instrument is equipped with a high-precision constant temperature circulation system, with a temperature control range of 25-45 ℃ and an accuracy of ± 0.1 ℃. Real time monitoring through multi-point temperature sensors ensures uniform and stable environmental temperature, simulating the physiological temperature of human skin.
The mixing system is equipped with imported micro motors, with a speed that can be infinitely adjusted between 50-500rpm. The mixing blades are made of polytetrafluoroethylene material and have no interaction with the receiving liquid. Smooth stirring without vortex, ensuring uniform concentration of the receiving liquid and significantly reducing test errors.
3、 Intelligent design empowers, simplifies operations and management
To improve efficiency, the instrument incorporates multiple intelligent designs. Equipped with a 10.1-inch color touch screen, the independently developed operating system supports one click setting and real-time display of test parameters (temperature, mixing rate, duration, etc.), with a simple interface that beginners can operate with simple training.
The instrument also has comprehensive data management functions, automatically recording key parameters (temperature curve, stirring rate curve, etc.), supporting Excel format export and storage, meeting the needs of data traceability and report generation. Some models reserve USB and Ethernet interfaces, which can be connected to LIMS systems to assist in the digital upgrade of laboratories.
4、 Flexible adaptation+thoughtful service to meet diverse needs
The instrument supports the replacement of various specifications such as Franz diffusion cell and vertical diffusion cell, and can choose channel configurations such as 2, 4, 6, and 8 to meet the needs of single sample repeated testing or multiple sample parallel testing, improving efficiency. The body is made of 304 stainless steel, which has undergone anti-corrosion treatment and is easy to clean and maintain, meeting the requirements of GMP clean laboratory.
In addition, Jingtuo Instrument provides comprehensive services, including free on-site installation and debugging, technical training, 1-year warranty, and lifelong technical support, allowing users to have no worries.
The Jingtuo Instrument Transdermal Diffusion Tester provides a reliable solution for transdermal drug delivery research with its "precision, stability, and intelligence" characteristics. In the future, Jingtuo will continue to innovate, optimize performance, and support the high-quality development of China's transdermal drug delivery industry.