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E-mail
benwu@aojizhineng.com
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Phone
18058851560
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Address
5th Floor, Building B, No. 580 Binhai 2nd Road, Longwan District, Wenzhou City, Zhejiang Province
Wenzhou Aoji Intelligent Technology Co., Ltd
Technical highlights and applications of pre filled syringe filling capping machine
Date: 2025-06-13Read: 4
1、 Equipment Overview
The pre filled syringe filling and capping machine is a core equipment in the field of biopharmaceuticals, dedicated to completing the integrated operation of quantitative filling of drugs, rubber stopper pressing, and aluminum cap tightening and sealing. It adopts modular design, meets GMP sterile requirements, and is suitable for the production of high-risk injections such as vaccines, monoclonal antibodies, and insulin.
2、 Core Technology Highlights
1. High precision filling system
By driving the piston pump with a servo motor, the filling accuracy can reach ± 1%. Combined with online weighing detection for real-time correction, it ensures that each syringe has a consistent filling volume. Some models use the time pressure method for filling, which is suitable for high viscosity liquid medicine.
2. Aseptic isolation technology
The filling area is equipped with laminar flow hoods and RABS (Restricted Access Barrier System), combined with VHP sterilization channels, and the environmental cleanliness meets ISO Level 5 standards. Key components such as the dispensing needle are made of 316L stainless steel material, which can withstand CIP/SIP cleaning and sterilization.
3. Intelligent screw cap control
Adopting a torque feedback system, the screw cap force is adjusted in real time to avoid glass breakage or leakage caused by excessive tightness or looseness. The visual system synchronously detects the integrity of the aluminum cover seal.
3、 Industry application value
Biopharmaceuticals: significantly reduce the risk of contamination in the production of cell therapy products.
Vaccine production: meets the particle control requirements of WHO for vaccine filling.
• Pre filled pen field: achieving efficient packaging of hormone drugs.
