Tosylate DPA-714 (CAS: 958233-17-5) is a highly selective TSPO ligand with pyrazolo [1,5-a] pyrimidine as its core. It has a molecular weight of 550.67 g/mol and is a off white solid with good organic solvent solubility. Its synthesis involves constructing a core skeleton through multiple reactions and introducing diethylaminoacetamide side chains and p-toluenesulfonic acid ester groups. The process is mature and supports customization. This compound is applied in the medical field as a PET tracer (such as [¹⁸ F] DPA-714), which can accurately image neuroinflammation, assist in early diagnosis and efficacy monitoring of diseases such as Alzheimer's disease and multiple sclerosis, and exhibit high in vivo stability and low non-specific binding in healthy volunteers. In addition, it can also be used for nanomaterial modification, cell culture, and metabolomics research. Storage should be refrigerated or frozen in the dark to avoid repeated freeze-thaw cycles.

CAS number: 958233-17-5

Reagent name: Tosylate DPA-714

Molecular weight: 550.67

Molecular formula: C29H34N4O5S

Appearance: Solid

Color: Off white to light yellow

Purity: ≥ 95%

Appearance: Solid powder or granules

Supplier: Xi'an Kaixin Biotechnology Co., Ltd

Structural formula:

Security protection:

During the operation, disposable protective clothing, masks and other protective equipment should be worn to ensure self safety.

This reagentonly useIn scientific research

Attention: When using, be sure to dry and avoid frequent dissolution and freeze-drying

【 Application 】

Nanotechnology and New Materials:

As a modifying component of nanoparticles or liposomes, it improves biocompatibility and targeting.

Used for developing multifunctional nanomaterials that combine imaging and therapeutic functions.

Cell culture and biological research:

As an additive in cell culture medium, it promotes cell growth and differentiation (such as stem cell culture).

Metabolomics and Mass Spectrometry Analysis:

Research grade products (purity ≥ 98%) support LC-MS/MS quantitative analysis and pharmacokinetic studies.

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The above content is edited and organized by YNN of Xi'an Kaixin Biotechnology Co., Ltd

This reagent is only used for scientific research experiments and cannot be used on the human body

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