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pharmamachBrand FaxWhat is the process principle of vacuum depressurization and concentration tank?
The process principle of vacuum depressurization concentration tank is based on the physical characteristics of boiling point changing with pressure, and achieves low-temperature and high-efficiency concentration by reducing system pressure. The following is a detailed explanation of its core process principle:
1、 Core principle
1. Pressure boiling point relationship: According to the Clausius Clapeyron equation, the boiling point of a liquid decreases exponentially with decreasing pressure. By using a vacuum pump to reduce the pressure inside the tank to below 1/10 of normal pressure (such as 0.09MPa), water can be boiled at 40-60 ℃ to avoid the decomposition of heat sensitive components.
2. Heat transfer enhancement: After decompression, the temperature difference of heat transfer increases by 3-5 times, and the evaporation efficiency is improved. However, it should be noted that the latent heat of vaporization increases by 12-18%, and the energy consumption is 25-40% higher than that of atmospheric evaporation.
2、 Process steps
1. Heating stage: Electric heating or steam heating of the liquid material to the target temperature.
2. Vacuum establishment: The vacuum pump unit is started to create a negative pressure environment (-0.08~-0.095MPa).
3. Solvent vaporization: The solvent evaporates at low temperatures, and the secondary steam is recovered through a condenser.
4. Concentrated liquid discharge: After reaching the target density, the concentrated liquid is discharged from the bottom conical structure to reduce dead corner residue.
3、 Equipment structure and process correlation
1. Concentrator tank: designed with a jacket or coil, with an increased heating area to improve efficiency.
2. Condensation system: A combination of tubular condenser and serpentine cooler ensures efficient steam recovery.
3. Vapor liquid separation: Install an air filter screen or extend the separation section at the top to prevent the entrainment of mist and foam.
4、 Key process parameters
1. Pressure range: industrial grade -0.05~-0.08MPa, experimental grade -0.08~-0.095MPa.
2. Temperature control: 40-60 ℃ (depending on the material) to avoid deactivation of thermosensitive components.
5、 Applicable materials and adjustments
1. Thermally sensitive materials: traditional Chinese medicine extracts, enzyme preparations, fruit juice, etc., require strict temperature control.
2. High viscosity materials: When the viscosity is greater than 500mPa · s, forced circulation is required to prevent coking, and when the solid content is greater than 30%, the process needs to be switched.

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