Intestinal Microecological Capsule Preparation Equipment Freeze Drying Machine

Intestinal Microecological Capsule Preparation Equipment Freeze Drying MachineUsing the feces of healthy donors as raw materials, the sterilization machine can automatically generate standardized bacterial solution once it is complete. Principle: Adopting cross flow, circulation, microporous membrane structure principle, temperature control, anaerobic. Due to the reasonable structure of the filter disk, it can automatically produce standard bacterial solution in 30 minutes with one click without centrifugation. The consumables are simple and easy to install, with good visibility and strong clinical adaptability. Advantages: No requirements for laboratory environment, fast and efficient bacterial production, abundant and high-quality bacteria, in line with the FMT standards issued by Shanghai, and is currently a high-quality product in China.

At present, there have been clinical observation studies on the treatment of various diseases with fecal bacteria transplantation, such as clostridium difficile infection, inflammatory bowel disease, hepatic encephalopathy, chronic hepatitis B, chronic constipation, chronic diarrhea, diabetes, fatty liver, autism, etc. Among them, fecal microbiota transplantation for the treatment of difficult to distinguish Clostridium infections has been included in clinical guidelines, and its efficacy has been fully recognized. The therapeutic effect of fecal microbiota transplantation on inflammatory bowel disease and hepatic encephalopathy has also been recognized.

The state of FMT can be divided into three forms: fermentation, fresh, and frozen. The routes of fecal microbiota administration are divided into three pathways: upper digestive tract, middle digestive tract, and lower digestive tract. The previous fecal microbiota transplantation process involved transferring fecal microbiota extract to the recipient through biwei tubes, endoscopic intestinal transplantation, or knotting. These methods were not only cumbersome but also invasive, resulting in low patient compliance and tolerance. Another method of fecal microbiota colonization is FMT fecal capsules, which to some extent avoids the drawbacks of the traditional methods mentioned above.

FMT fecal capsule is a method of freeze-drying donor fecal samples after standardized fecal sampling, and developing them into powder and capsule packaging for oral administration by patients. This method can maintain the bacterial activity and diversity of fecal microbiota, and has the advantages of safety, convenience, and speed.

Intestinal Microecological Capsule Preparation Equipment Freeze Drying MachineIt is carried out at low temperatures, making it particularly suitable for heat sensitive substances such as microbial communities. During the freeze-drying process, malignant mutations and bacterial contamination of the microbiota cannot occur, thus maintaining the original characteristics of the microbiota. The freeze-dried microbial community freeze-dried powder is loose and porous, sponge like, and dissolves rapidly, almost immediately restoring its original characteristics. Freeze drying is carried out under vacuum, with minimal oxygen and sufficient protection of bacterial activity. Freeze drying can remove more than 95-99% of moisture, and the dried microbial products can be stored for a long time without deactivation or deterioration.