Thermo Fisher mass spectrometer

Highlights of Orbitrap IQ-X Tribrid Mass Spectrometer

Automated and user-friendly software simplifies setup and data collection

The instrument control software uses pre built templates and readily available experimental parameters, designed to help you quickly analyze complex samples. Use dedicated Auto Ready ion source hardware for automated instrument calibration to ensure that the instrument is ready when you set it up.

Thermo Fisher mass spectrometer

Intelligent collection can collect more valuable data

The intelligent real-time library retrieval and AcquireX data collection tool can automate MSn data collection, improve analysis efficiency, and help you obtain more compounds with identifiable fragments for more in-depth analysis.

Data analysis tools can perform fast, flexible, and in-depth analysis

A comprehensive and integrated data collection and analysis tool that enables you to quickly generate informative and reliable MSn data based on complex samples.

Liquid chromatography-mass spectrometry (LC-MS) software tool for structural analysis of MSn data

LC-MS software tools include MSn mass spectrometry trees, novel spectral prediction techniques, computer simulation fragmentation modeling, and precursor ion fingerprinting display, which can help you identify known substances and analyze the structure of unknown substances.Thermo Fisher mass spectrometer

Hardware and Data Acquisition Technology

The hardware design of the instrument and the efficient and comprehensive data acquisition workflow make the Orbitrap IQ-X Tribrid mass spectrometer the preferred solution for small molecule identification, characterization, and quantification.

Instrument hardware design and intelligent data acquisition

The mature Tribrid architecture combines quadrupole, linear ion trap, and Thermo Scientific Orbitrap HRAM technology to obtain rich MSn data in each sample. Multiple fragmentation techniques, including collision induced dissociation (CID), high-energy collision dissociation (HCD), and optional ultraviolet photodissociation (UVPD), can be used at any stage of MSn, and subsequent mass analysis can be performed in ion traps or ultra-high resolution Orbitrap mass analyzers.

The reason why the Orbitrap IQ-X Tribrid mass spectrometer can obtain reliable results is due to its flow technology. The Auto Ready ion source is calibrated and maintained with specialized hardware specifications to ensure consistent performance throughout its entire lifecycle. The Thermo Scientific EASY-IC ion source uses a second ion source to generate specific calibration ions, adjusting the instrument's mass accuracy in real-time to less than 1 ppm, and correcting the mass accuracy of scanned changes and deviations. Advanced quadrupole technology includes segmented quadrupole mass filters, which can achieve high transmission with a narrow isolation width as low as 0.4 m/z, improving sensitivity and selectivity. At m/z 200, the ultra-high field Orbitrap analyzer can achieve a resolution of up to 500000, distinguishing between target ions and interfering ions. For fine isotope structures, the optional resolution can reach up to 1000000 (1M) resolution. The dual pressure linear ion trap can provide the highest MSn rate of 45Hz and perform sensitive mass analysis on three complementary cleavage types: CID, HCD, and optional UVPD.