Ultra high resolution mass spectrometry system

Orbitrap Excedion ProUltra high resolution mass spectrometry system

Orbitrap Exceeding Pro is a flagship two in one mass spectrometry platform aimed at multiple fields such as biopharmaceuticals, proteomics, metabolomics, and structural biology. With performance innovation, mass spectrometry technology has entered a new journey.

Product Features:

·Enhanced Orbitrap technology, innovative breakthrough: fast and highly sensitive new fragmentation technology, enhanced ion optical components, improve scanning speed and data quality, and provide excellent analysis results.

·Comprehensively improving the characterization level of biopharmaceuticals: Reliable characterization of intact proteins under Nature and denaturation conditions, with a quality detection range of up to m/z 12000, and enhanced sequence coverage through high-energy collision dissociation (HCD), optional electron transfer dissociation (ETD), and EThcD combined fragmentation mode. Combined with its wide dynamic range scanning mode, it has high sensitivity and is particularly suitable for analyzing post-translational modifications (PTMs) and identifying structural isomers.

·Assisting in deeper proteomics research: The dynamic range of a single scan is wider, up to five orders of magnitude, which can improve the detection and quantification performance of low abundance proteins and post-translational modifications (PTMs) in MS full scan mode; Supports up to TMT Pro ™ 32 standards, significantly improving protein identification flux

·Further exploration of metabolomics and lipidomics research can be achieved through the design of an electric ion funnel, which can minimize accidental fragmentation, protect the integrity of fragile metabolites, and ensure improved signal-to-noise ratio of precursors. Enhanced dynamic range (eDR) scanning function can improve the signal-to-noise ratio of low abundance compounds in complex mixtures without affecting the detection of high abundance samples, increasing the sample coverage depth by another order of magnitude, achieving high sensitivity and specificity detection and quantification of multiple metabolites.

Orbitrap Excedion ProUltra high resolution mass spectrometry systemApplication Scenario:

·Biopharmaceuticals: Comprehensive structural characterization and post-translational modification (PTM) analysis of oligonucleotide and antibody drug conjugates

·Proteomics: Research on post-translational modifications (PTM), identification of structural isomers, protein conformational changes, and intermolecular interactions

Multi omics research: metabolomics research, lipidomics research, exposure omics research.

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