GMP has the following requirements for pharmaceutical water preparation equipment:

1. The structural design should be simple and easy to disassemble and assemble.

2. To facilitate disassembly, replacement, and cleaning of parts, the design of the actuator should use standardized and universal components as much as possible.

3. The inner and outer wall surfaces of the equipment should be smooth and flat, easy to clean and sterilize. The surface of the parts should be treated with chrome plating or other surface treatments to resist corrosion and rust. Avoid using paint on the outside of the equipment to prevent peeling.

4. The preparation of purified water equipment should use low-carbon stainless steel or other materials that have been verified to not pollute water quality. The equipment for preparing purified water should be regularly cleaned and the cleaning effect should be verified.

5. The material in contact with injection water must be low-carbon stainless steel or other materials that have been verified not to pollute the water quality. The equipment for preparing injection water should be regularly cleaned and the cleaning effect should be verified.

6. The storage period of purified water should not exceed 24 hours, and its storage tank should be made of stainless steel material, corrosion-resistant, and other materials that do not leak out pollutant ions. A hydrophobic sterilization filter with non shedding fibers should be installed to protect its ventilation port. The inner wall of the storage tank should be smooth, and there should be no dead corners or sand holes in the connecting pipes and welds. Sensors that do not cause stagnant water pollution and display parameters such as liquid level, temperature, and pressure should be used. Regularly clean, disinfect and sterilize storage tanks, and verify the effectiveness of cleaning and sterilization.