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The use and classification of mixers in the pharmaceutical industry
Date: 2024-09-14Read: 10
The nature of the pharmaceutical industry is relatively special, and the quality requirements for pharmaceutical equipment are also very high. Any mistake in any link may lead to drug quality problems, causing serious consequences.
A mixer is a machine that uses mechanical force and gravity to evenly mix two or more materials. Hybrid machinery is widely used in various industries and daily life. The commonly used mixers are divided into four categories: gas and low viscosity liquid mixers, medium high viscosity liquid and paste mixing machines, thermoplastic material mixers, and powder and granular solid material mixing machines.
The main components of the mixer are made of alloy materials, including high-speed mixing blades, mixing fins, liners, mixing arms, mixing shovels, planetary shovels, mixing plows, mixing bars, mixing rakes, and other mixing machinery for medium and high viscosity liquids and pastes, which generally have strong shear effects.
For intermittent operation, it also includes machinery that has both mixing and grinding functions, such as wheel rollers.
The moving parts of a mechanical mixer also produce shear effects on the liquid during rotation. When the liquid flows through the wall of the mixer and various fixed components installed in the container, it also experiences shear effects, which can cause many local vortex diffusion.
For liquids with different densities, compositions, and immiscibility, the shear effect and strong turbulence generated by stirring tear the high-density liquid into small droplets and evenly disperse them into the main liquid.
The maintenance steps for the mixer are as follows:
① The machine needs to be used frequently, and the gearbox needs to be replaced with new oil every three months. When replacing, the gearbox should be cleaned and filled with new oil.
② The equipment components should be inspected 1-2 times a month, including the worm gear, worm gear, bearings, and oil seals. The operating parts should be checked for flexibility, and the fasteners should be checked for looseness. Any abnormal situations should be promptly addressed.
③ If the machine vibrates abnormally or makes abnormal sounds during use, it should be stopped immediately for inspection.
④ Electrical control components should be kept clean and sensitive, and any malfunctions should be promptly repaired.
⑤ When assembling and disassembling the mixing slurry, it should be dismantled gently, installed steadily, and placed gently to avoid deformation and damage.
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