Avestin production type high-pressure nano homogenizer cell disruptor

manufacturer:Avestin Inc.，Ottawa，Canada
Ovstein Corporation (Canada)Avestin）HighPressureHomogenizer
Ovstein Corporation (Canada)Avestin）EmulsiFlex-C160Principle of homogenizer:
Entering the homogenization valve at high pressure and low flow rate generates extremely intense energy, which is accompanied by shear, cavitation, and impact effects to crush solid particles and cells.

Product Parameters

1.Work pressure: from0to30,000PSI（0~207Megapascals), continuously adjustable
2.Flow characteristics: continuous flow, pressure can be gradually adjusted freely
3.Ultra large processing capacity:160L/h
4.Ultra small sample size:40ml
5.Pump power source: power driven,380V,50Hz/60hz,11kW
Product Features
1.Good homogeneity reproducibility and stability
2.Optional flow control system and temperature control system
3.The product channel adopts a special conical seal, which is easy to disassemble and has no vulnerable gaskets, avoiding secondary pollution
4.The body components are made of pharmaceutical grade stainless steel. Acid resistant, alkali resistant, high temperature resistant, corrosion-resistant, and highly wear-resistant
5.Suitable for products such as fat emulsions, liposomes, lipid nanoparticles, and nanosuspensions
6.Optional heat exchanger,The homogenization process is less than0.1second,The product has a small temperature rise
7.Can be cleaned online and sterilized in place. The product can be used throughout the entire processSIPHigh pressure sterilization or steam sterilization, including all wetted parts
8.Can be combined with online extrusion system,The extrusion pressure for homogenization is provided by homogenization power
9.The product meets hygiene standardsGMPstandard
Ovstein Corporation (Canada)Avestin）We have experimental, pilot, and production high-pressure nano homogenizers to choose from, with flow rates ranging from7Milliliters per hour to2000Rising per hour, the ultra-high working pressure can reach3100Bar(310MPa)The ultra-high pressure nano homogenizer. From product pretreatment to homogenization and homogenization treatment, Jungao Biotechnology can provide a range of services.
Ovstein Corporation (Canada)Avestin）High pressure homogenizer highlights its advantages
Mainly used for:Cell lysis, liposomes, emulsions, dispersions, graphene, bamboo fibers, various fluids, etc

Cell fragmentation:
1Brucella cells require15000Psi（1000Bar）-17000Psi（1180Bar）Broken under pressure.
2：PicciaYeast and mycobacteria>22000Psi（1500Bar）Broken under pressure.
3Pear wine (yeast)Schizosaccharomycescells in28000Psi（1900Bar）Broken under pressure
4Bamboo fiber25000Psi（1700Bar）Broken under pressure
5Graphene is28000Psi（1900Bar）Broken under work pressure
6The wall breaking rate can reach99%The above.
Liposomes: in15000Psi（1000Bar）Under homogenization, it can also be homogenized through a filter extruder (passing through a polycarbonate membrane)+Extrusion can be used to prepare50nmThe80nmThe100nmThe200nmYou can also choose the following liposomes without loss1Milliliter hand push liposome extruder or pneumatic50Milliliter liposome extruder, polycarbonate membrane with diameter19mmThe25mmThe47mmThe90mmThe142mmThe293mmWait until it can be prepared15nmThe30nmThe50nmThe80nmThe100nmThe200nmThe following liposomes.
Homogenization, emulsion: generally in10000Psi（700Bar）-20000Psi（1400Bar）Formed below, it can reach the nanometer level.
Dispersion: Generally with a diameter of10-100umUnder the circumstances, to5000Psi（350Bar）Run it once first, smash the large particles, and then25000Psi（1700Bar）Processing the dispersion can reach the nanometer level
Structural features: High precision structure, product channels without gaskets andOCircle; All core components are imported with reliable performance, and the homogeneous chamber is always guaranteed.
Equipment and materials:316LStainless steel17-4PHStainless steel, ceramics, diamonds; Acid and alkali resistance, high temperature resistance, strong wear resistance, strong tensile strength, and corrosion resistance