7500+LC-MS/MS liquid chromatography-mass spectrometry analyzer

AB Sciex Triple Quad ™ The 7500+LC-MS/MS liquid chromatography-mass spectrometry system is a high-performance triple quadrupole mass spectrometry systemUltra high sensitivity and high-throughput analysisandIntelligent workflowAs a core advantage, it is widely used in fields such as pharmaceuticals, food safety, and environmental monitoring. The following is a detailed introduction to its core performance:

1、 Core technical parameters and hardware configuration

1. Ion source and ionization technology

• OptiFlow ™ Pro ion sourceCompatible with flow rates ranging from 1 µ L/min to 3 mL/min, no need to adjust probe position, supports fast switching between ESI/APCI, significantly improving ionization efficiency.

• E Lens ™ technologyBy optimizing the ion focusing path, the sensitivity is improved from microliters to conventional flow rates, and the detection limit is as low as sub picograms (such as 0.1 pg fipronil).

2. Quality Analysis System

• Triple quadrupole designQuality range 5-2000 Da, scanning speed up to 5000 amu/sec, support16384 MRM channels synchronously monitoredMeet the demand for high throughput.

• D Jet ™ Ionic guidance technologyCapture more ions and reduce background noise, with a dynamic range of6 orders of magnitudeEnsure low concentration quantification accuracy.

3. Gas chromatography module

• Integrated high-performance liquid chromatography system, with a column temperature chamber heating rate of 125 ° C/min, supporting rapid separation (such as completing analysis of 16 PAHs within 9 minutes).

2、 Intelligent and efficient functions

1. QTRAP ® Ready Technology

• Upgradeable to a composite linear ion trap system, supporting MRM ³ mode, enhancing signal-to-noise ratio and selectivity in complex matrices.

2. SCIEX OS software platform

• Unified control of data collection, processing, and audit tracking, built-inReal time Multi Correction (RT-MRM)Function, simplify method development.

3. Automated maintenance

• Self cleaning ion source probe and remote diagnostic function reduce downtime and maintenance costs by 30%.

3、 Application scenarios and performance advantages

1. Pharmaceutical and Biomedical

• Meets the requirements for detecting 33 types of pesticide residues, supports pharmacokinetic (PK) and bioequivalence (BE) studies, and has a sensitivity of 0.01 ng/mL.

2. food safety

• According to the EU SANTE/11813/2017 standard, over 200 pesticide residues can be screened simultaneously, with a quantification limit as low as 0.1 pg.

3. environmental monitoring

• Detecting 117 VOCs specified by EPA 8260B, the sensitivity of dioxin analysis reaches 0.25 pg, suitable for trace analysis of POPs and heavy metals.

4、 Scalability and compatibility

• modular designSupports accessories such as headspace injection and direct injection rods, seamlessly integrating UHPLC systems (such as ExionLC AD).

• Multi ionization modeOptional APCI/APPI source to expand the analysis capability of thermally unstable compounds.

summary

Triple Quad ™ 7500+with D Jet ™ Ionic guidance, 16384 MRM channel, and QTRAP ® Upgraded functionality, particularly suitable for complex matrix analysis with high regulatory requirements in the industry in terms of sensitivity (Afik level), flux (5000 amu/sec scan), and long-term stability. Its intelligent software and low maintenance design further enhance laboratory efficiency.