Laboratory room temperature ultrafine grinder

Jinan Dawei Machinery Co., Ltd. is a professional company that specializes in the research and development, design, production, and sales of advanced equipment that can perform cell level ultrafine grindingEnterprise.

The company specializes in micro (nano) Rice noodles technology, process, equipment and technical services, and undertakes the research of related topics of the Chinese medicine pharmaceutical powder engineering department. The vibrating ultrafine crusher was successfully developed in 1996, and technical engineers from the company's R&D department participated in the design and development of the vibrating ultrafine crusher. Until now, we have been committed to the research and development, design, updating and improvement of ultrafine grinding equipment and cell wall breaking equipment. From the single XDW-6 series and XDW-F (L) 100 series model specifications to the current XDW-2 series, XDW-6 series, XDW-9 series, XDW-15 series, XDW-30, XDW-40 series, XDW-70 series, XDW-F100 seriesXDW-Z100 seriesVarious models and specifications such as XDW-L100 series, XDW-L200 series, XDW-L400 series are available for users to choose from. In terms of material, a new ceramic series equipment with zero metal mixing has been developed from the original pharmaceutical grade stainless steel material, which meets the requirements of customers' products; Known as "green ultrafine grinding equipment and technology".

Laboratory room temperature ultrafine grinderIt belongs to the fourth generation vibration mill and has the characteristics of high crushing efficiency, high wall breaking rate, low crushing temperature (temperature controllable), efficient crushing, no residue residue, fully enclosed operation, and no material loss. The particle size of the powder can reach 1-0.1 μ m, and the cell wall (membrane) breaking rate is over 98%. Nowadays, Dawei ultrafine grinding and cell wall breaking technology have been widely used in industries related to powder applications such as medicine (including veterinary drugs and pesticides), food (food), cosmetics, chemical building materials, metallurgical energy, electronic environmental protection, and resources, and have gained recognition and good reputation from a large number of users.

Dawei Machinery - Cell level Ultra fine Grinding

Laboratory room temperature ultrafine grinderThe pulverization operation that improves the bioavailability of traditional Chinese medicine by breaking the cell wall (membrane) of animal (plant) medicinal materials is called traditional Chinese medicine cell level micro pulverization. The vast majority of traditional Chinese medicine varieties come from animals (plants). Animal (plant) medicinal materials are composed of cells with multiple functions, including cell wall, cell membrane, cytoplasm, nucleus, etc. The particle size is generally between 10 μ m and 100 μ m, and the medicinal active ingredients mainly exist in the cytoplasm and nucleus. In the intact and undamaged state of cells, effective ingredients can only be utilized after being released through the cell membrane and cell wall. The complete cell membrane and cell wall form resistance to the release of active ingredients, and this resistance increases sharply with the increase of the number of cells in the cell mass. The medicinal active ingredients mainly exist within the cell - between the cytoplasm and the nucleus. Due to the dual effects of the inward resistance of the cell wall (membrane) and the coagulation resistance of cell aggregates (coarse powder), the active ingredients are difficult to release and be absorbed by the body or intestines, which is an important reason for the large and unclear dosage of traditional Chinese medicine. To eliminate this resistance, a micro crushing process should be adopted to break down the cells so that the active ingredients inside the cells can directly contact the solvent. This type of homework is not aimed at fineness, and fineness is only used as a macroscopic detection method, which cannot express the true situation of medicinal powder. Generally speaking, the higher the cell wall breaking rate, the finer its fineness. After breaking through the cell wall, the active ingredients inside the cell are fully exposed (instead of being released through the cell wall [membrane] as before), making the drug more effective.

working principle

The Dawei Mechanical Ultra fine Grinding Equipment belongs to the new fourth generation vibration mill. It adopts multiple advanced technologies and applies high-speed impact force and shear force according to the different characteristics of the material, so that the material is subjected to high acceleration impact, friction, compression, cutting and other effects of the medium in the grinding cylinder, and can achieve ideal grinding effect in a short time. The material becomes fluidized during the crushing process, so that each particle has the same stress state, achieving precise mixing (dispersion) effect while crushing. By adjusting parameters such as acceleration, it is possible to achieve operations with the goal of crushing and grinding or precision mixing (blending) as the main objective.

The device adopts the working principle of vibration crushing, filling the grinding medium such as hard material balls, rods or columns in the grinding cylinder (crushing chamber). The grinding cylinder produces circular vibration in the clockwise and counterclockwise directions as shown in Figure 1 under the action of external excitation force. The strong vibration of the grinding cylinder causes the medium inside the grinding cylinder to produce a throwing motion. Under the action of this throwing motion, each medium produces a rotation in the same direction as the circular vibration. At the same time, the medium group also produces 3-5 cycles of low-frequency vibration opposite to the circular vibrationturnMove. So the medium sometimes disperses and sometimes collides with each other, producing a positive impact force p and a lateral shear force L on the material as shown in Figure 2. The material is finely ground, broken, and crushed under the impact, compression, and shear forces of P and L.

The Dawei ultrafine grinding series equipment has the following characteristics

The parts in contact with the material are all polished stainless steel, which is a universal material for medical and food machinery (can also be changed to other metal materials according to user requirements), to avoid the mixing of heavy metals such as arsenic, cadmium, mercury, lead, copper, etc.

2. Cleanliness and hygiene: Smooth inner and outer surfaces, versatile use of one machine, reduced pollution, and reduced cleaning workload; The crushing process is fully enclosed without dust spillage, fully improving the working environment, and effective ingredients are not lost.

3. Adopting a composite (transparent) soundproof cover greatly reduces noise.

4. Easy to disassemble (assemble), easy to clean, and easy to change materials. Can be cleaned and disinfected with water, compressed air, alcohol, steam, etc.

5. Easy to operate: Capacity adaptation, ensuring material discharge, easy operation and material replacement.

6. Easy maintenance: compact structure, small footprint, and convenient maintenance.

7. Improving the environment: Fully enclosed operations with dust spillage, no loss of active ingredients, and no generation of drug residues can improve the working environment.

8. Efficiency: Crushing, no residue left. The bidirectional effect of high-speed impact force and shear force shortens the crushing time and improves the crushing efficiency.

9. Broad spectrum adaptation: Suitable for any fibrous, high toughness, high hardness, or moisture content material. For pollen and other sporeszhiMaterials that require breaking the cell wall have a breaking rate of over 98%. Adapt to both dry and wet crushing simultaneously. Water, alcohol, or other liquids can be added during wet crushing.

10. Temperature controllable: Through configuration, micro crushing can be carried out at high temperature, room temperature, and low temperature, which can maintain the original physicochemical properties and active ingredients of the material. Inject cold water into the jacket on the outer wall of the grinding cylinder. The crushing temperature can be controlled by adjusting the temperature and flow rate of the cooling water. Low temperature crushing, the freezing system can reach a low temperature of minus 35 ℃ (low-temperature configuration).

Solved various problems in traditional Chinese medicine crushing operations

Strong fibrous (such as Ganoderma lucidum, licorice, etc.), high sugar and high viscosity (such as goji berries, Ophiopogon japonicus, etc.)

Resin based materials (such as frankincense, myrrh, etc.) have strong toughness (such as seahorses, etc.)

Animals (such as scorpions, leeches, etc.) and minerals (such as *, cinnabar, etc.)