Laboratory ultrafine crusher

NegotiableUpdate on 02/11

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Nature of the Manufacturer: Producers

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Overview

Broad spectrum adaptation: Suitable for any fibrous, high toughness, high hardness, or moisture content material. Materials that require breaking of cell walls, such as pollen and other spore materials, have a breaking rate of over 98%. Adapt to both dry and wet crushing simultaneously. Water, alcohol, or other liquids can be added during wet crushing. Laboratory ultrafine crusher

Product Details

Laboratory ultrafine crusher-Cell level ultrafine pulverization

The pulverization operation that improves the bioavailability of traditional Chinese medicine by breaking the cell wall (membrane) of animal (plant) medicinal materials is called traditional Chinese medicine cell level micro pulverization. The vast majority of traditional Chinese medicine varieties come from animals (plants). Animal (plant) medicinal materials are composed of cells with multiple functions, including cell wall, cell membrane, cytoplasm, nucleus, etc. The particle size is generally between 10 μ m and 100 μ m, and the medicinal active ingredients mainly exist in the cytoplasm and nucleus. In the intact and undamaged state of cells, effective ingredients can only be utilized after being released through the cell membrane and cell wall. The complete cell membrane and cell wall form resistance to the release of active ingredients, and this resistance increases sharply with the increase of the number of cells in the cell mass. The medicinal active ingredients mainly exist within the cell - between the cytoplasm and the nucleus. Due to the dual effects of the inward resistance of the cell wall (membrane) and the coagulation resistance of cell aggregates (coarse powder), the active ingredients are difficult to release and be absorbed by the body or intestines, which is an important reason for the large and unclear dosage of traditional Chinese medicine. To eliminate this resistance, a micro crushing process should be adopted to break down the cells so that the active ingredients inside the cells can directly contact the solvent. This type of homework is not aimed at fineness, and fineness is only used as a macroscopic detection method, which cannot express the true situation of medicinal powder. Generally speaking, the higher the cell wall breaking rate, the finer its fineness. After breaking through the cell wall, the active ingredients inside the cell are fully exposed (instead of being released through the cell wall [membrane] as before), making the drug more effective. After the drug particles were finely ground at the cellular level, a small amount of intact cells were observed under electron microscopy.

working principle

Laboratory ultrafine crusherIt belongs to the new fourth generation vibration mill, which adopts multiple advanced technologies and applies high-speed impact force and shear force according to the different characteristics of the material, so that the material is subjected to high acceleration impact, friction, compression, cutting and other effects of the medium in the grinding cylinder, and can achieve ideal powder crushing effect in a short time. The material becomes fluidized during the crushing process, so that each particle has the same stress state, achieving precise mixing (dispersion) effect while crushing. By adjusting parameters such as acceleration, it is possible to achieve operations with the goal of crushing and grinding or precision mixing (blending) as the main objective.

The working principle of vibration crushing is adopted, and grinding media such as hard material balls, rods or columns are filled in the grinding cylinder (crushing chamber). Under the action of external excitation force, the grinding cylinder produces circular vibration in the clockwise and counterclockwise directions as shown in Figure 1. The strong vibration of the grinding cylinder causes the medium inside the grinding cylinder to undergo a throwing motion. Under the action of this throwing motion, each medium produces a rotation in the same direction as the circular vibration. At the same time, the medium group also produces 3-5 low-frequency rotations opposite to the circular vibration. So the medium sometimes disperses and sometimes collides with each other, producing a positive impact force p and a lateral shear force L on the material as shown in Figure 2. The material is finely ground, broken, and crushed under the impact, compression, and shear forces of P and L.

model project		XDW-6B Micro Ultra fine Grinding Machine (Low temperature Cell Wall Breaking Machine)
host system	purpose	This device can be used for ultrafine grinding (cell wall breaking). It can be applied to the crushing of any fibrous, blocky, viscous, tough, extra hard and other materials.
	Power KW	1.1KW (voltage: three-phase four wire 380V)
	main bearing
	Nominal volume	6.3L
	Grinding cylinder wall thickness	12mm
	Flip limit	Double helix type
	flipping mechanism	Fully enclosed structural support
	Vibration isolation device	Specially made 60Si2MnA vibration isolation spring, 2 pieces for left and 2 pieces for right rotation. This design has a national technical certificate for vibration isolation components and crushers.
	Grinding material	Food and drug grade high-quality 304 stainless steel
	Medium size	Diameter 20X174mm
	Grinding method	Vibration type
	amplitude	6mm adjustable
	barrel	2 pieces
	Loading quantity	1.2L
cooling system	Low temperature configuration	Fully enclosed three horsepower, -20 to -25 degrees Celsius, imported (joint venture) compressor
	Cooling method	Low temperature freezing
	Power KW	2.4KW (three-phase four wire 380V)
	Water jacket	External water jacket with insulation
	Cooling method	Cooling liquid circulation cooling
	Cooling water connection method	Low temperature rubber hose+rubber insulation pipe connection
	thermostat	have
electrical appliance control		Important components are produced using imported technology, while the rest are domestically produced
Drive connection method		Belt type soft connection (more suitable for the flexibility and stable performance of experimental equipment power), this design has transmission components and national technical certificates for crushers.
Other parameters	soundproof enclosure	Low noise stainless steel composite soundproof cover
	Overall dimensions	Host: L1030 × W750 × H1500 Refrigerator: L1100 × W720 × H930mm
	Weight (KG)	Host: 480KG Refrigerator: 250KG
Equipment Technology		1. Fully enclosed non graded technology: The fully enclosed multi grinding non screening technology used to preserve the active ingredients effectively avoids phenomena such as segregation and loss of active ingredients, and environmental pollution caused by dust spillage. 2. Compression micro crushing technology: In order to improve the crushing efficiency and effectiveness, high-speed impact force and shear force are used to subject the material to the squeezing, kneading, and tearing effects of the medium in the grinding cylinder, greatly shortening the crushing time and improving the crushing efficiency; At the same time, due to the fluidized state of the material and the same stress state of each particle, its own viscous effect can form uniformly dispersed and precisely composite particle clusters in the finished product, increase density and improve bioavailability, and enhance micro crushing efficiency and technology. ★ 3. In order to improve the efficiency of crushing and wall breaking, and ensure the stable performance of equipment operation, the driving connection is designed as a soft connection and equipped with an eccentric block. The output shaft of the driving component is connected to the eccentric block through a soft connection to drive the vibration of the grinding cylinder. This design has obtained the national technical certificate for the transmission components of the crusher and the crusher. 4. Dynamic optimization technology: a technology that optimizes and adapts according to the different characteristics of materials while ensuring the improvement of micro crushing efficiency and effectiveness. 5. Mechatronics technology: a technology that achieves high performance and level of equipment, reduces manual labor, ensures stable and controllable product quality, and avoids quality instability and pollution caused by excessive manual intervention. 6. Comprehensive automation technology: equipped with single machine multifunctional automation (FMC flexibility), making small-scale drug production as simple as large-scale assembly line production. 7. Clean and safe technology: The Dawei ultrafine grinder series is designed and manufactured strictly in accordance with GMP standards, which can meet the special requirements of pharmaceutical powder equipment.
Equipment features		1. Strong safety: The parts in contact with the material are all polished stainless steel, which is a material commonly used in international medical and food machinery (can also be changed to other metal materials according to user requirements), to avoid the mixing of heavy metals such as arsenic, cadmium, mercury, lead, copper, etc. 2. Cleanliness and hygiene: Smooth inner and outer surfaces, versatile use of one machine, reduced pollution, and reduced cleaning workload; The crushing process is fully enclosed without dust spillage, fully improving the working environment, and effective ingredients are not lost. 3. Adopting a composite (transparent) soundproof cover greatly reduces noise. 4. Easy to disassemble (assemble), easy to clean, and easy to change materials. Can be cleaned and disinfected with water, compressed air, alcohol, steam, etc. 5. Easy to operate: Capacity adaptation, ensuring material discharge, easy operation and material replacement. 6. Easy maintenance: compact structure, small footprint, and convenient maintenance. 7. Improving the environment: Fully enclosed operations with dust spillage, no loss of active ingredients, and no generation of drug residues can improve the working environment. 8. Improve efficiency: high crushing rate, no residue left. The bidirectional effect of high-speed impact force and shear force greatly shortens the crushing time and improves the crushing efficiency. ★ 9. Broad spectrum adaptation: It can adapt to any fibrous, high toughness, high hardness, or material with a certain moisture content. For materials such as Ganoderma spore powder and other spore plants that require breaking the cell wall, the breaking rate shall not be less than 99.5% (as evidenced by the testing breaking rate report issued by an edible mushroom testing center with CMA and CATL qualifications). Adapt to both dry and wet crushing simultaneously. Water, alcohol, or other liquids can be added during wet crushing. ★ 10. Temperature controllable: Through innovative configuration, micro crushing can be carried out at high temperature, room temperature, low temperature or ultra-low temperature, which can maintain the original physicochemical properties and active ingredients of the material. Grind at room temperature and introduce cooling water into the jacket on the outer wall of the grinding cylinder. The crushing temperature can be controlled by adjusting the temperature and flow rate of the cooling water. The low-temperature ultrafine grinder has low-temperature or ultra-low temperature function (low-temperature ultrafine grinder is a product with a national technical certificate for low-temperature ultrafine grinder), and the freezing system temperature can reach minus 25-35 ℃ (B and C series high-end low-temperature configurations, J and A series do not have low-temperature function).
Material adaptation		Widely used as a single or compound powder for animal, plant, mineral, and traditional Chinese medicine, especially suitable for strong fibrous and tough plants. High sugar viscous materials with a content of over 15% require a refrigeration system
Capacity kg/h		Ordinary Chinese medicinal materials (food) 0.5-1.5kg/h, -300 mesh 90-98%. The yield of Ganoderma spore powder is 0.4-0.6kg/h (2500 mesh), with a wall breaking rate of 90-98%.
Technical Support		Independently developed and produced, with at least five relevant product technical certificates
Export standards		Compliant with EU export standards, with CE certificate and quality management system certificate
Honors and Qualifications		The manufacturer has a credit rating of AAA or above and a certificate
Overall appearance of the machine		Full stainless steel appearance
Place the venue		Can be placed in GLP laboratories or 100000 level GMP cleanrooms
delivery cycle		20 working days
Other instructions		Power supply: 3-phase/380; Circulating cooling system